L3: Cell Signalling and the Cell Cycle in Cancer

Question 1

What type of signals regulate the cell cycle?

Answer 1

Positive and negative signalling

Question 2

Which cell cycle phase is responsive to mitogens?

Answer 2

G1 phase

Question 3

What are the phases of the cell cycle?

Answer 3

• G0
• G1
• S
• G2
• M

Question 5

What type of signals regulate the cell cycle?

Answer 5

Positive and negative signalling

Question 6

Which phase of the cell cycle is responsive to mitogens?

Answer 6

G1 phase

Question 7

What are the phases of the cell cycle?

Answer 7

• G0
• G1
• S
• G2
• M

Question 8

Which is the quiescence state?

Answer 8

Non-dividing (resting) state is G0

Question 9

What are the features of G1 phase?

Answer 9

Growth phase 1, cell growth and preparation for DNA synthesis
- responsive to environmental signals
- contains G1 resitriction checkpoint (R)
- G1/S DNA damage checkpoint

Question 10

What are the features of S phase?

Answer 10

Synthesis phase, DNA replication

Question 11

What are the features of G2 phase?

Answer 11

GRowth phase 2, preparation for mitosis, checkpoint for DNA damage before entering M phase

Question 12

What happens during M phase?

Answer 12

mitosis, nuclear division