L3 Caries Flashcards
Acidogenic
Acid producing: drive down pH
S. Sanguis
S. Mutans
Development and composition of biofilm
SS binds to pellicle via adhesions
Sm binds to Ss via adhesions
Sm uses Glucosyltransferease to make extracellular matrix of sucrose/glucan
Sm attaches to glucan via glucan binding protein
S. Sanguinis vs S mutans at pH levels
Ss is better at High
Sm is better at Low b/c can ferment sugars at low
Aciduric
Can survive in low pH
S. Mutans is acquired around
26 months
Targets for Caries vaccine to S mutans
Glucosyltransferase
Glucan binding proteins
Mucosal vaccination thru nasal and ingestion is an example of
Active immunity
Antibodies from tobacco, cow milk are examples of
Passive immunity
STAMPS stands for
Spefically Targeted AntiMicrobial Peptides