L3 Bias Flashcards

1
Q

selection bias

A

choosing participants who may influence the study results

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

how to avoid selection bias

A

using random sequence generation and allocation concealment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

random sequence generation

A

researchers randomly assign participants into groups, should be computer generated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

allocation concealment

A

the person randomising the participants to experimental and control groups could not predict what group the person will be allocated to

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

performance bias

A

when participants know which group they are assigned to, it can change their responsesor behaviour and affect the outcome of the study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

how to control for performance bias

A

conduct a double blind study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

detection bias

A

when the person or people measuring te outcomes knows which participants received the intervention

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

how to control for detection bias

A

conduct a double-blind study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

attrition bias

A

the differences between experimental and control groups because of withdrawals from the study

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

how to contol for attrition bias

A
  • Explain the reasons for withdrawal and account for all the data
  • Authors must do an ‘intention to treat’ analysis - analyse all the data available from the study cohort – those who enrolled at the beginning.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is reporting bias

A
  • Differences between reported and unreported findings
  • Statistically significant differences between intervention groups are more likely to be reported than non-significant differences
  • Emphasising positive findings while downplaying negative findings
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

how to spot reporting bias

A

when there are multiple research questions outlines and yet the study does not report an answer for all of them

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

most common type of bias

A

reporting bias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

placebo effect

A

the participant feeling improved even though they recieved a placebo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

nocebo effect

A

participant feeling disimproved even though they haven’t taken anything (see coke contamination story)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

single-blind study

A

participant does not know which intervention they received (real or placebo)

17
Q

double-blind

A

neither particpant nor researcher know which intervention the participant received (real or placebo)

18
Q

what is the CASP checklist

A

Tool used for readers to help critical appraisal

19
Q

what does CASP stand for

A

critial appraisal skills prgramme

20
Q

what are CONSORT guidelines

A
  • Reporting guideline which authors should follow when publishing their RTC