L286 Why Exercise? Flashcards

1
Q

Exercise capacity and mortality: evidence for relationship

A

• ↓ MET → ↑ risk of death, ↑ MET → ↑ years of life gained, ↓ mortality

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2
Q

Physical activity and obesity: relationship

A

• ↓ physical activity, ↑ obesity

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3
Q

Role of sitting in ill-health

A

• ↑ sitting (even if active), ↑ risk of death

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4
Q

Comment on the possible role of an ‘exercise pill’ as therapy

A
  • AMPK and PPARδ agonists are exercise mimetics - but does it work?
    • They may be mimetics, but its not possible to re-capitulate all factors of exercise
  • However, might this be useful as adjunct therapy (e.g. in people who cannot exercise)
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