L286 Why Exercise? Flashcards
1
Q
Exercise capacity and mortality: evidence for relationship
A
• ↓ MET → ↑ risk of death, ↑ MET → ↑ years of life gained, ↓ mortality
2
Q
Physical activity and obesity: relationship
A
• ↓ physical activity, ↑ obesity
3
Q
Role of sitting in ill-health
A
• ↑ sitting (even if active), ↑ risk of death
4
Q
Comment on the possible role of an ‘exercise pill’ as therapy
A
- AMPK and PPARδ agonists are exercise mimetics - but does it work?
- They may be mimetics, but its not possible to re-capitulate all factors of exercise
- However, might this be useful as adjunct therapy (e.g. in people who cannot exercise)