L23 Antibiotic prophy Flashcards
1
Q
Progression of subacute bacteria endocarditis
A
Extraction produced bacteremia Antibodies bind Ab/bacteria circulates Infect sterile thrombus on diseased tissue Infection
2
Q
What requires prophy
A
Cardiac valve
Previous infective endocarditis
Cardiac transplant patients W/ VALVE DEFECTS
Congenital heart defect repaired with pros material (6 months)
Defect in prosthetic repaired heart
3
Q
How long to get endocarditis
A
Bacteremia within 15 minutes
4
Q
Prophylaxis with suture removal
A
Not required
5
Q
Prophy regimen
A
2gm amoxicillin 1 hour pre op
1gm ampicillin IV or IM 30 min pre-op
6
Q
Prophy is allergic to PCN
A
Clindamycin 600mg 1 hr pre-op
7
Q
If already on PCN what drug should you avoid
A
Cephalosporin
8
Q
Patient with non coronary vascular grafts
A
Prophy for 6 months
9
Q
Prophy doses (MIC)
A
Prophy: 4x MIC and 2x therapeutic
10
Q
Why amoxicillin
A
GI absorption
High plasma level
Long half life from single dose
Slow excretion
