L21 - Lipid Metabolism 1

Question 1

What are TAGs composed of?

Answer 1

A glycerol linked to 3 FAs

Question 2

What does lipolysis do?

Answer 2

It releases the FAs so they can be used for B-oxidation

Question 3

Apart from FAs what does lipolysis produce?

Answer 3

The other product of lipolysis = glycerol. This can be converted to DHAP and:

i) used for energy production by glycolysis or
ii) used as a substrate for gluconeogenesis

Question 4

What 2 enzymes are used to break down lipids?

Answer 4

• DAG lipase

- TAG lipase

Question 5

Describe the steps of how a TAG gets to a FA

Answer 5

TAG ——> DAG (via TAG lipase)

DAG ——> MAG (via DAG lipase)

MAG + H20 ——> FA (via MAG lipase)

Question 6

Where does B-oxidation take place in eukaryotes and prokaryotes?

Answer 6

E: In the mitochondria - it is only done aerobically
P: cytoplasm

Question 7

What carrier is used to carry the Fatty Acyl CoA?

Answer 7

Carnitine

Question 8

Describe how FAs are activated in the cytoplasm

Answer 8

g