L20 Endocytosis Flashcards
What is endocytosis?
Endocytosis is a cellular process by which cells take in substances from their external environment.
As if cells are eating/drinking on a microscopic level
What can be taken up in endocytosis? (7)
Nutrients
Signals
Antibodies
Enzymes
Viruses
Bacteria
Membrane
What are the different fates that endocytosed material can have?
Recycling
Transcytosis
Degradation
What are the multiple endocytic pathways?
Small - scale endocytic processes (Clathrin)
Macropinocytosis
Phagocytosis
What are endocytosis pathways? (G= Gemini)
What is opsonization? And how does it relate to phagocytosis? (G)
What is frustrated phagocytosis?
Both phagocytes may attempt to engulf the bacterium, but neither is able to fully internalize it
What was the first hint that membrane recycling occurs with beads? (G and PowerPoint)
What’s the difference between macropinocytosis and phagocytosis?
Specificty: M- non specific, P - specific
Particles engulfed: M- Fluid and solutes, P- large particles
Mechanism: Membrane ruffling, P - Membrane end tension
Vesicle size: M- Large, P- small
What does LDL stand for?
How does Clathrin mediated endocytosis work? (I’ll do this)
What’s the structure of Clathrin? (G)
What’s the similarity of all the 3 endocytic pathways that we need to know? (G)
All 3 have a pinching motion
What is dynamin and what is it required for?
How does actin relate to the 3 endocytic pathways?
