L2- Flow Mechanics From Air To Cell Flashcards
Simple Diffusion features
Aka: FLUX
Passive process- No ATP required
Down conc gradient (fluid)
Down partial pressure (gas)
Only v small molecules can pass through this easily
E.g. C02, 02 and lipid soluble substances
Flow- features
Requires ATP
E.G. Blood moving through capillaries
Movement of gases in and out of alveolus
VENTILATION
Ficks Law
Membrane factors - determines how much of a gas can pass through a membrane
Or
Rate of diffusion of a gas across a membrane is
-DP to SA
-DP to conc gradient
- IP to thickness of membrane
Diffusion Coefficient
Depends on solubility and molecular weight of gas
How are gases carried in the blood
- Plasma
- Chemically altered/modified
- Protein bound
Why do we need bulk/CONVECTIVE flow
Because diffusion is only good over short distances
Terrible over long distance- would take way too long
Flow equation
Change in pressure \ resistance
Systemic circulation
LHS
Pumping oxygenated blood to RHS
E.g. Of where flow is needed in the body
In RS and CVS- partial pressure gradients are created- ATP needed for this to occur
Osmosis
Net movement of water over a selectively permeable membrane from an area of high water potential (low solute conc) to area of low water potential (high solute conc).
How to STOP osmosis
Make membrane impermeable
Make the concentration of solutés equal on both sides -
Reverse osmosis
Reverse!!
Tonicity
The ability of extra cellular solution to make water move in or out of a cell
Isotonic
Conc of solute is same inside and outside cell
Thus no osmosis occurs
Cell size stays the same
Hypotonic
Solute conc is greater inside the cell
Water molecules can move in and out
BUT: will find it harder to move out as the solute molecules will be blocking them
Thus more water molecules move IN
Cell size increases as water moves INTO cell by osmosis
Hypertonic
Higher solute concentration outside cell
Water molecules move in and out
But will find it harder to move in as solute molecules block them
Thus more will move OUT by osmosis
Cell size decreases
How to remeber : hypertonic : e for exit : OUTSIDE
Clinical application of tonicity
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