L2

Question 1

How does the distribution of cells differ in necrosis vs. apoptosis

Answer 1

necrosis = usually continuous 
apoptosis = usually single cells affected

Question 2

How does the size/shape of cells differ in necrosis vs. apoptosis

Answer 2

necrosis= swollen

apoptosis=shrunken & convoluted

Question 3

How does the nuclear morphology of cells differ in necrosis vs. apoptosis

Answer 3

necrosis= lysed
apoptosis= condensed chromatin & fragmented nuclei

Question 4

How does the plasma membrane of cells differ in necrosis vs. apoptosis

Answer 4

necrosis= damaged/ leaky 
apoptosis= intact until phagocytosed

Question 5

How does the cytoplasm of cells differ in necrosis vs. apoptosis

Answer 5

necrosis= contents released 
apoptosis= retained in apopopoptic body

Question 6

How does inflammation differ in necrosis vs. apoptosis

Answer 6

necrosis= present
apoptosis= absent

Question 7

How do cells undergo apoptosis?

Answer 7

normal&raquo_space; cell skinkage and chromatin condensation&raquo_space; membrane blebbing&raquo_space; nuclear collapse&raquo_space; apopoptic bodies form&raquo_space; lysis of bodies

Question 8

What is the best definition of cell injury

Answer 8

failure of a cell thorough damage to mechanisms maintaining homeostasis