L10- Role of pathology Flashcards
1
Q
What are the layers of the colon?
A
Mucosa
Sub-mucosa
Muscularis
Serosa
2
Q
What are the Dukes stages?
A
Stage A - confined to bowel wall not spread to serosa
Stage B - spread through thickness of bowel wall into serosa
Stage C - Spread to lymph nodes
Stage D - spread to other tissues e.g. liver
3
Q
What is immunohistochemistry?
A
The use of labelled antibodies to identify specific antigens such as specific to cancers. flourescent labeing may be used.
4
Q
What is FISH?
A
In situhybridisation is much less frequently used and recognises specific RNA or DNA sequences.
Can be used to identify Kappa and Lamda chains or RNAs encoded by the epstain barr virus.
