L10 - Linkage and chromosome mapping in eukaryotes Flashcards
1
Q
At meiosis in the formation of human gametes, how many chiasma can be formed between non-sister chromatids?
A
1-3 chiasma
2
Q
What is homologous recombination?
A
Genetic recombination in which nucleotide sequences are exchanged between two very similar or identical molecules of DNA (e.g. region of the same DNA sequence)
3
Q
What is heterologous recombination?
A
Genetic recombination in which nucleotide sequences are exchanged between two similar molecules of DNA (e.g. region of similar DNA sequence)
4
Q
In eukaryotes, mutation in DNA repair enzymes leads to…
A
Cancer
5
Q
Formula for Recombinant Frequency
A
Recombinant Frequency = (number of recombinants/total number of progeny) x 100
