L1 Introduction to Infection and Immunity Flashcards

1
Q

World wide infection death

A

1/3

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2
Q

Healthcare associated infection [6]

A
Nosocomial (hospital acquired) pneumonia 
Staph Aureus 
Clostridium Difficile 
Enterococcus 
Wound infection 
Implant infection
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3
Q

1:4 Deaths in the UK

A

18-19th century

Mycobacterium TB

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4
Q

Bacteria

A
Binary Fission 
Maybe mobile - flagella 
Mycoplasma and chlamydiae are wall deficient 
Spirochetes - treponema pallidum 
Rickettsia and actinomyces
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5
Q

Candida species

A

Albicans -> yeast

unicellular & reproduce by budding

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6
Q

Aspergillus species

A

Fumigatus -> mould, multicellular

Reproduce by spores

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7
Q

Protozoa

A

Entamoeba histolytica - amoebic dystentry

Plasmodium Falciparum - malaria

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8
Q

TB decline due to

A

natural selection

resistance polymorphisms

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9
Q

Tolerance

A

A state of immunological non-reactivity to antigen

Our proteins, harmless environmental antigens and commensal

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10
Q

Taxonomy

A

Genus first

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11
Q

Pneumococcus

A

Streptococcus pneumoniae

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12
Q

Meningococcus

A

Neisseria Meningitidis

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13
Q

E coli O157:H7

A

Haemolytic uraemic syndrome

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14
Q

S pyogenes M3T3

A

Toxic shock syndrome

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15
Q

Prokaryotes

A
Bacteria, archaea (blue-green algae) 
70s ribosomes (50s + 30s subunit)
No nucleus 
Non-genetic DNA
Peptidoglycan cell wall
Haploid
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16
Q

Eukaryotes

A

Fungi (candida), protozoa and helminths

Membrane bound nucleus, 80s (60s and 40s)

17
Q

Round

A

Coccus/cocci

Streptococcus and enterococcus

18
Q

Long

A

Bacillus/bacilli

Enterobacter

19
Q

Gram staining

A

Fixation - crystal violet - iodine - decolourise - counter stain (safranin)
Purple = gram +ve
Pink = gram -ve

20
Q

Switch between anaerobic and aerobic respiration

A

Facultative anaerobes

21
Q

Nutritional requirements of bacteria

A

Purine/pyrimidine, amino acid and vitamins

e. coli = glucose + inorganic salt –> easy growth
treponema pallidum = specialised, enriched medium. Hard to grow fastidious