L01: Fundamental Concepts of Pharmacology Flashcards
Drugs
chemicals that exhibits a specific response after absorption/digestion.
Drugs: derived from a ____ word “____” which means
Drugs: derived from a Dutch word “Drogue” - dried medical plants
Pharmacology:
study/science of drugs on the LIVING systems
Pharmacology includes (3) of a drug
(incl. Hx, sources, properties (Phys/Chem) of a drug) :
pharmacology is derived from a greek word “______” meaning
pharmacology is derived from a greek word “Pharmakon” - drugs
Pharmacogenetics:
study of the different responses of an individual in a certain drugs as influenced by its genes.
Genetic Factor can ____________the absorption of drugs ➡️_______
Genetic Factor can INFLUENCE/AFFECT the absorption of drugs ➡️side effects
Pharmacognosy:
study of natural drugs (plant-based or animal-based) : natural resources
Pharmacy:
science of preparing, compounding (i.e. mixing, combining or altering), and safe dispensing of drugs
Toxicology:
study of harmful effects of drugs on living things (i.e. humans)
Posology:
study of dosage/quantity of drugs given to pt to get the right pharmacological effect
Therapeutic effect:
desired/primary effect why we are taking the drugs
Side effect:
unintended/secondary effect of the drugs (expected)
Adverse effect:
harmful and undesirable effect of the drugs (unexpected)
Drug allergy:
immunologic reaction of the body to a drug
drug allergy is caused by
hypersensitivity or presence of antibody as a result of previous exposure to a certain drugs.
most common allergic reaction to drugs
- Hives (irregular raised patterns)
2. Urticaria (severe itching)
Anaphylactic reaction:
severe reaction after drug administration
anaphylactic reaction is considered ______ because it can cause _____
life-threatening
respirtory distress & CV collapse
use to treat anaphylactic reaction
Epinephrine
Drug tolerance:
pt requires higher dose
Drug tolerance is usually caused by
psychological dependency or faster drug metabolism
Cumulative effect
e.g.
occurs when the drug is not yet metabolized or in the peak of its therapeutic effect and you take another dose of it = increasing response
alcohol - drug & CNS depressant = slows down brain func
Drug abuse:
use of illegal/OTC drugs