L&J Chp 4 Monitoring Anesthetized Patients Flashcards
PaCO2
- Measure of the effective alveolar minute ventilation
- Normal: 35-45mm Hg
How anesthesia changes PaCO2
Values may be higher in anesthetized patients with up to 60-80 mm Hg in horses and cattle
PaCO2 >60mm Hg
- May be associated with excessive respiratory acidosis
- Usually considered to represent sufficient hypoventilation –> warrants PPV
PaCO2 <20 mm Hg
- Associated with respiratory alkalosis
- Decreased cerebral blood flow –> may impair cerebral oxygenation
Causes of hypocapnia/hyperventilation
- Light level of anesthesia
- Hypoxemia
- Hyperthermia
- Hypotension
- Inappropriate ventilator settings
- Early pulmonary parenchymal disease
Postop Causes of Hypocapnia/Hyperventilation
- Excitement stage of recovery
- Delirium
- Pain
- Distended urinary bladder
- Sepsis
Causes of hypercapnia/hypoventilation
- Excessive depth of anesthesia
- NM disease
- Airway obstruction
- Pleural space-filling disorder
- Late pulmonary parenchymal disease
- Inappropriate ventilator settings
- Malfunctioning anesthetic machine
Malfunctioning/incorrectly used anesthetic machine causing hypercapnia/hypoventilation
- Unidirectional gas flows stuck
- Absorbent exhaustion
- Low FGF with non-rebreathing circuits
What are the two types of capnometry?
- Time capnometry (time:PCO2)
2. Volume capnometry (volume:PCO2)
Capnometry
- Measure of CO2 in the respiratory gases
Methods of measuring gaseous carbon dioxide
- Infrared light absorption (most common)
- Raman spectroscopy
- Mass spectroscopy
Infrared light absorption
Absorption is proportional to the partial pressure of the gas
Raman spectroscopy
- Monochromatic argon light beam passed through the gas sample
- Light is absorbed, re-emitted at a different wavelength that is specific to the gas molecule that absorbed it
Mass Spectroscopy
- Based on separation of various gas species by an electron beam in an magnetic field
- Expensive, bulky, not commonly used in clinical practice
Time capnography
- PCO2 expressed as a function of time during the respiratory cycle
- Used to verify correct ETT placement, CPR, assess adequacy of ventilation
Volumetric (Volume) capnography
- plots expired CO2 against time
What can the volumetric capnography determine?
VT Anatomic, alveolar, physiologic dead space Effective alveolar VT ETCO2, PaCO2 eliminated CO2 volume Mixed-expired CO2
Volumetric capnography: flattening of curve
AKA less steep phase II coupled with less plateaued phase III
Suggests increased physiologic deadspace either due to lower airway obstructive disease or to increased alveolar headspace ventilation (PTE, hypovolemia)
What would cause the volumetric capnography waveform to drop to zero?
Accidental extubation
Cardiac arrest
What effect does PPV have on the volumetric capnography waveform?
May either flatten the slope due to increased alveolar dead space ventilation or normalize the slope due to recruitment of collapsed lung units
What are the four phases of a capnograph waveform?
Phase 1 - inspiratory baseline
Phase 2 - transitional phase/expiratory upstroke
Phase 3 - expiratory plateau/alveolar gas
Phase 0 - inspiratory down stroke
Significance of the alpha angle
Change from airway gas to alveolar gas
Normal 100-110*
Increased angle - airway obstruction, VQ mismatch
Significance of the beta angle
ETCO2/max alveolar CO2 concentration
Normal approx 90*
Increased by rebreathing
Characteristics Light Plane Anesthesia
Central eye position \+ Palpebral Medium to large pupil size \+ PLR Moist corneas Lots of eyelid/mandibular muscle tone \+/- reflex movement response to nociception \+ physiologic response to nociception