L&D Complications Flashcards
Preterm labor
Labor before 37 wks; preterm ctx / pain (vs cervical insufficiency)
Risk of preterm labor
High risk of small baby (IUGR, SGA = small for gestational age, whereas LBW = < 2500 g)
Preterm labor is associated with:
PROM, chorioamnionitis, multiple gestations, uterine anomalies, previous preterm delivery, small mom,
abruption, PEC / maternal infection, surgery, low SES
If preterm labor + fever, need to:
Do amniocentesis to rule out chorioamnionitis before giving steroids for lung maturity
Preterm contraction management
Don’t do tocolysis unless there’s cervical change (no labor unless the cervix is changing). Instead, observe.
What is the point of tocolysis
xTrying to buy yourself 48h for betamethasone if < 34 wks for lung maturity
Beta-mimetics
Ritodrine (is only FDA approved tocolytic) - continuous IV
Terbutaline - load, then q3-4h
increases ATP → cAMP
SE/CI of beta-mimetics
SE: Tachycardia, H/A, anxiety, pulmonary edema
CI: diabetes
SE/CI of Mag Sulfate
SE: Flushing, H/A, fatigue, diplopia, Lose DTRs (<10), respiratory depression, hypoxia → cardiac arrest (>15)
Contraindicated in myasthenia gravis
Mag Sulfate
“tocolytic” but no evidence that it actually delays anything
Ca+ antagonist
Ca-channel blockers
Nifedipine
SE: H/A, flushing, dizziness
Prostaglandin inhibitors
Indomethacin
Don’t use close to term (PDA closure)
Also pulm HTN, oligo 2/2 renal failure, increased risk necrotizing enterocolitis & intraventricular hemorrhage
NSAIDs - block COX
Benefits of Betamethasone
RDS prevention
Decreased intracerebral hemorrhage and necrotizing enterocolitis in the newborn
It has not been associated with increased infection or enhanced growth.
PROM
> 1h prior to labor
biggest risk is for chorio
Often induce if > 34-36 wks
prolonged PROM
> 18h = prolonged PROM
chorio risk increased > 18h; give abx ppx if expecting prolonged ROM