Kulkarni Yellow Book Flashcards
What condition has eczema, thrombocytopenia and immunodeficiency associated with it?
What is the platelet size?
What its inheritance pattern and how is it cured?
Wiscott Aldrich
Small platelets
Inherited X-linked so boys are more affected
Stem cell transplant
For a child with HCM who had chest pain twice in the setting of exercise over the past 3 months, what’s the next best step in management?
Beta blockers to decrease heart rate and improve ventricular filling
If the patient had had a documented arrhythmic event, then an AICD - automatic impantable cardioverter defibrillator would be recommended.
When a facial palsy involves the ENTIRE right side of a face. Is it central or peripheral?
What then is the most likely etiology if accompanied by malaise and myalgia.
It is peripheral. Lyme disease a cause of PERIPHERAL facial palsy when accompanied by fatigue and myalgia
In central disease, there is forehead sparing.
A baby with Beckwith-Wiedemann disorder presents with large tongue, neonatal hypoglycemia and is LGA. Which tumors are they at risk for?
Wilms tumor, hepatoblastoma, rhabdomyosarcoma, neuroblastoma. Routine ultrasounds are recommended. The hypoglycemia that occurs is transient and due only to pancreatic cell hyperplasia NOT any insulin mass
What is the Kocher criteria for evaluating a septic hip vs transient synovitis?
Temp > 101.3F
WBC > 12 K
ESR > 40mm/h
Inability to ambulate.
Absence of all four makes the likelihood of septic arthritis 0.2%
What is the treatment for transient synovitis?
NSAIDs
What is the treatment for transient synovitis?
NSAIDs usually x 7-10 days
What is a typical WBC of synovial fluid in a septic joint?
More than 50,000 cells/mm
OPEN fractures can be classified using the Gustilo and Anderson classification system to decide on appropriate antibiotic choice.
True. The single most important factor in reducing infection rates is early administration of prophylactic antibiotics within 3 hours.
If the open fracture has a wound LESS than 1 cm with minimal contamination, soft tissue damage and no comminution then IV cefazolin (1st gen cephalosporin) is appropriate.
If the wound is > 1 cm or there is moderate or more soft tissue damage or periosteal stripping or MORE then the appropriate prophylaxis is: IV cefazolin + aminoglyside (gentamicin)
Why is enoxaparin preferred to IV heparin?
It is easier to give outpatient. It only requires once or twice daily monitoring of Xa after initiation but IV heparin requires q6h monitoring of PTT.
However, LMWH is only partially reversible with protamine and has a longer onset of action
In the management of bronchiolitis, which of the following 2 is recommended by the AAP (chest PT or nebulizer hypertonic saline)?
Nebulized hypertonic saline
What is the most helpful way to rule out T1DM and determine Type 2 DM in a new diagnosis of DM?
The absence of pancreatic ISLET cell autoantibodies (e.g IA2, GAD, Zinc transporter 8)
A 9 month old boy with L arm abscess, recent otitis media and pneumonia, loose malodorous stools, hepatomegaly with elevated ALT, Thrombocytopenia, mild anemia, neutropenia, FTT, is concerning for
Schwachman diamond which is associated with pancreatic insufficiency. They are at risk long term of MDS and AML.
Treatment for the condition includes GCSF, pancreatic enzyme replacement and stem cell transplant.
Tetralogy of fallot spells happen because crying or agitation/stress increases PVR which worsens RV outflow obstruction and causes increased R to L shunting. What is the treatment?
Oxygen, morphine to help with relaxation and phenylephrine to increase SVR. Can also consider fluid bolus to increase RV filling.
Prostaglandins do not have any role in managing tet spells except at the very beginning of life to keep PDA open to minimize impact of severe RVOT obstruction
Even if motivated by religious preference, if a family understands the benefit of a treatment like insulin and refuses it for their child, the best action is to
Report it to CPS for medical neglect
What test is dilute Russell viper venom used for?
To diagnose antiphospholipid syndrome
A 6 wk old is brought to ED for 2 wks of vomiting. She has been tracking along the 50%ile for wt, episodes of emesis are 5-6 times a day occurring 20 to 30 min after feed. Never bloody or bilious and she is in no pain during worries. She has 3-4 stools per day. What’s best next step?
No testing is needed. She has reflux.
What do Heinz bodies indicate?
G6PD or oxidative damage to RBCs
What is ristocetin cofactor testing used for?
VWD
Reactions to contrast are anaphylactoid not IgE mediated. They can have tachycardia, urticaria, bronchospasm, laryngospasm and the reaction can be prevented by using a steroid. A reaction to contrast that includes hypertension is more physiologic and would not be prevented by a steroid.
Repeat.
An egg shaped cardiac silhouette on CXR in a neonate with hypoxia suggests transposition of the great arteries (the most common CYANOTIC congenital heart defect) that usually requires the PDA to stay open to oxygen prevent mixing.
Repeat
Organophosphate are commonly found in pesticide or fertilizer. The toxidroe associated with them include mnemonic DUMBBBELS (defecation, urination, miosis, bronchorrhea, bronchospasm/cough, bradycardia, emesis, lacrimation/watery eyes, salivation/drooling). Also weakness, paralysis. They are cholinesterase inhibitors and lead to increase acetylcholine activation in synapses. It should be treatment with anticholinergic like atropine.
Repeat
What is Sturge Weber syndrome and what is it associated with?
Neurocutaneous disorder associated with port wine stain (vascular malformation of face) with leptomeningeal angiomas of brain and eye. If the port wine includes the ophthalmic branch (upper branch) of the trigeminal nerve then they have a 50% risk of glaucoma and 10-35% risk of brain involvement.
What is Sturge Weber syndrome and what is it associated with?
Neurocutaneous disorder associated with port wine stain (vascular malformation of face) with leptomeningeal angiomas of brain and eye. If the port wine includes the ophthalmic branch (upper branch) of the trigeminal nerve then they have a 50% risk of glaucoma and 10-35% risk of brain involvement.
What genetic disease is associated with cardiac rhabdomyosarcomas?
Tuberous sclerosis
In Williams syndrome, what electrolyte abnormality can be seen?
Hypercalcemia
What bacterial cause of osteomyelitis is a gram negative coccobacillus?
Kingella Kingae - can be a/w mouth ulcers.
Prior to vaccination, Hib which was the same morphology, was more commonly implicated.
A 7 year old with a doughnut shaped mass protruding from the urethra with erythema and a small amount of bleeding (that falsely appeared vaginal prior to exam) has what?
How is it treated?
Urethral prolapse
Treatment: sitz bath and estrogen cream
Most common aged 4-8yrs
Enterococcus is resistant to: cephalosporins, often to bactrim, and is not treated with gentamicin motherly. Best treated with ____
Ampicillin
In a patient with acute bone or soft tissue infection concern in the lower extremity, what study should be obtained first?
Plain X-rays
What is the empiric treatment for erythema migrans?
Amoxicillin or doxycycline for 10-14 days for early localized disease
Or 14-28 days for early disseminated and late disease (depending on the specific extracutaneous disease).
You can do antibody testing in patients who lack the characteristic rash.
What is a normal CRP range?
0.8-1.0mg/dL or 8-10mg/L
What are the classification for determining degree of envenomation from a snake bite and at what level would anti-venom be considered?
None/dry bite: only snake puncture wounds, no surrounding erythema, no systemic systems or lab abnormalities.
Mild: puncture wounds with local erythema, edema, ecchymosis or pain. No systemic or lab abnormalities
Moderate: puncture wounds with progression of edema or erythema but not involving whole extremity. Systemic
Symptoms: n/v, metallic taste, oral paresthesias, tachycardia, tachypnea, mild hypotension. Abnormal coagulation labs (elevated PT time, low platelets).
Severe: puncture wounds, significant erythema, edema, ecchymosis of extremity, blisters and necrosis. Systemic symptoms: n/v, metallic taste, oral paresthesias, tachycardia, tachypnea, mild hypotension +/- serious bleeding. Labs: abnormal coagulation labs (elevated PT time and low platelets)
Consider antivenom in patients with moderate to severe envenomation.
A patient with recent diagnosis of sinusitis who was on amoxicillin develops fever, headache, left arm weakness, AMS, and vomiting? What has happened and what is the right antibiotic choice?
What is the classic triad?
The patient has developed a brain abscess. The right treatment is ceftriaxone and flagyl for common causes (strep, staph, anaerobes, gram negatives). Gentamicin and cefazolin (1st gen cephalosporin) are not used because they have poor CNS penetration.
Triad: fever, headache, and focal neurological deficits
Peritonsillar abscesses are more common than RPAs.
RPAs can spread to the mediastinum as a complication.
Both abscesses are usually polymicrobial.
Peritonsillar abscesses greater than 1 cm need surg intervention
All true.
What does CHARGE syndrome stand for?
Coloboma of the eye, heart anomalies, choanal atresia, retardation, genital and ear anomalies.
You can distinguish this from DiGeorge because there’s eye involvement in only one of them
What are the findings in DiGeorge syndrome?
Thymic aplasia/hypoplasia, parathyroid aplasia or hypoplasia - leading to hypopara, cardiac defects, developmental delay, facial features (bulbous nose etc).
What coagulation study should be severely elevated in hemophilia A (the severe type) and what is the treatment?
PTT should be elevated and the treatment is Factor 8.
A child with acute kidney injury, micoangiopathic hemolytic anemia and thrombocytopenia.
What infection is most likely responsible?
When does HUS develop relative to primary infection with strep?
Shiga toxin producing E Coli (STEC) - 90% of case. Also strep pneumoniae and HIV are other acquired causes.
Hereditary causes are usually due to complement gene mutations or inborn errors of Cobalamin C.
Develops 3-13 days after the primary infection with strep
A polycyclic rash with central clearing that spares the palms and soles of the feet and can present with fevers, facial and actual edema with antibiotics as a common trigger is …
Serum sickness like reaction. Management includes antihistamines and NSAIDs. If severe case, can consider steroids.
What is the most common autosomal dominant form of hereditary pancreatitis?
It’s PRSS1
What genes are associated with Alagille syndrome?
JAG1 and NOTCH2
A patient with asthma who goes from having a respiratory alkalosis and metabolic acidosis to a hyperbaric respiratory acidosis suggests you need to prepare to get…
An advanced airway
A 1 yr old with history of FTT presents with a femur fracture in the ED and the xray shows osteopenia. What should be checked?
Serum and urine electrolytes to rule out Fanconi syndrome (proximal renal tubular acidosis)
What is the empiric treatment for PID? Usually caused by Gonorrhea, chlamydia or anaerobes?
Options are Doxycycline and cefoxitin/cefotetan OR
Clindamycin and gentamicin
OR (Unasyn + Doxycycline)
Only for mild PID: azithromycin +/-metronidazole
Floroquinolones are not appropriate due to resistant gonorrhea.
A sexually active teen patient with 4 days of knee and ankle joint swelling, conjunctivitis and sacroilitis with normal WBC, normal ESR and mildly elevated CRP without recent diarrhea or urinary symptoms is concerning for…
Reactive arthritis which is likely due to chlamydia trachomatis. Had he had diarrhea, it would have been due yersinia, campylobacter, salmonella, or shigella.
What is wet wrap therapy?
Medium potency corticosteroids or emollients followed by two layers of gauze or two layers of cotton pajamas. For gauze or PJs - inner layer is wet and outer layer is dry.
A hemodynamically unstable patient with mid-gut malrotation needs what emergently?
Fluid resuscitation and then emergent surgical exploration
What heart rate threshold should prompt concern for rentrang SVT?
Older child: above 180bpm
Infant: above 220bpm
A patient with moderate acute asthma exacerbation experiences a transient drop in oxygen 30 minutes into treatment with albuterol starting. What’s the next step in management?
Give supplemental oxygen, this hypoxemia comes from V/Q mismatch due to systemic absorption of beta agonist which causes pulmonary vasodilation to previously poorly ventilated areas of the lung. It is transient and oxygen responsive with no new fatigue, or altered mental status from hypercarbia.
Parotitis due to a sialolith can be managed with…
If no pus or concern for infection then sialologogues like lemon, or glandular massage posterior to anterior on the SAME side that is affected.
What popular class of drugs is contraindicated in asthma patients?
Beta blockers like propranolol
What popular class of drugs is contraindicated in asthma patients?
Beta blockers like propranolol
The presence of what physical exam findings rule against testicular torsion?
Negative Doppler, normal testicular lie, normal cremasteric reflex
Epipidymitis in a non sexually active male who is not at risk of UTI is most likely viral
Supportive care
In a sexually active male, UTI due to G/C is treated with?
If they have insertive anal sex, they are at increased risk for GNRs and could be treated with?
Ceftriaxone/Azithromycin or ceftriaxone/doxycycline for G/C
For GNRs, levofloxacin
A 4 yr old male is admitted for his fifth admission to manage constipation in 2 years. He passed meconium at 30 hours of life. Has occasional abdominal pain and has been compliant with all meds. What does he have?
Less severe Hirschprung’s disease
A 3 yr old male is admitted for pneumonia. He has had recurrent otitis media and sinusitis and this is his 3rd admission for pneumonia. He does not have tonsils on exam. What is his condition? How is the diagnosis confirmed?
His condition is X-linked agammaglobuniemia and the diagnosis is confirmed by a mutation in the gene responsible for BTK kinase so B-cells and thus immunoglobulins are missing. The adenoids and tonsils are B-cell rich.
A 3 yr old male is admitted for pneumonia. He has had recurrent otitis media and sinusitis and this is his 3rd admission for pneumonia. He does not have tonsils on exam. What is his condition? How is the diagnosis confirmed?
His condition is X-linked agammaglobuniemia and the diagnosis is confirmed by a mutation in the gene responsible for BTK kinase so B-cells and thus immunoglobulins are missing. The adenoids and tonsils are B-cell rich.
What condition is a dihydrorhodamine assay useful to diagnose?
It is useful to diagnose CGD in patients with recurrent pneumonias and skin infections. Patients typically have hepatomegaly, splenomegaly, or lymphadenitis
Hypoaldosteronism is associated with what electrolyte derangements? …
Hyponatremia, hyperkalemia, acidosis.
For classic CAH: males can have a normal exam or darkened scrotum and enlarged phallus. Females can have clitoral enlargement or labial fusion.
A torn lingual frenulum in a non ambulatory infant (e.g. 8 week old) should prompt concern for…
NAT and if the child is irritable, consider a head CT
How is nephrotic syndrome defined?
> 300mg/dL of urinary protein, or loss of more than 3g in 24hrs
A patient with history of obliterative bronchiolitis, bronchiectasis, allergic rhinitis and chronic diarrhea who is underweight and has sinus tenderness and prudent rhinorrhea is concerning for
Selective IgA deficiency
If a patient ingests lighter fluid (hydrocarbon), they are at risk of aspiration pneumontis and need to be observed. Only if fever persists for more than 48 hrs should bacterial superinfection be considered.
True.
A patient with acute asthma exacerbation who suddenly on hospital day 3 develops a new oxygen requirement with bilateral crackles and wheeze on exam is concerning for…
Pulmonary edema and could benefit from a one time diuretic.
For acute bacterial cervical lymphadenitis, is there any specific sized abscess that should prompt image guided aspiration or surgical drainage?
No! They should first fail 2nd or third line antibiotics after 48-72hrs before intervention. E.g. if only on augmentin, add MRSA coverage.
What are the indications to remove a central line in the setting of CLABSI?
Line is broken irreparably, patient is significantly ill appearing, infection is disseminated, cannot clear bacteremia after 48-72h, or evidence of fungal disease
A 2 week old on newborn screen has elevated TSH, the newborn is well appearing. What could most likely give a false positive result?
Maternal history of graves. TSH does not cross the placenta but maternal antibodies from graves can.
According to IDSA, abscesses that lack systemic signs and aren’t in an immunocompromised person should be managed with …
I&D
HyperIgE is a recurrent infection syndrome that is a rare autosomal
Dominant condition where patients have recurrent skin and pulmonary infection (chronic dermatitis, upper airway infections, sinusitis and AOM) an and eczema due to impairment in JAK STAT pathway. Abnormalities in osteoclastogenesis and osteopenia lead to skeletal and dental anomalies
True
What is the gold standard test for myocarditis?
Endomyocardial biopsy NOT echocardiogram
A 2 yr old child admitted with respiratory distress who has history of constipation, frequent bouts of coughing, failure to thrive and whose CXR shows nearly opacified L Lung that responds well to chest PT, antibiotics and supplemental
Oxygen should be evaluated for…
Cystic fibrosis
A 5 year old girl who has presented with 3 bouts of not feeling well and emesis after a night of not eating well with low blood glucose of 45 is concerning for?
What laboratory abnormalities should be found?
Ketotic hypoglycemia of childhood
Labs should show high ketones, high fatty acids, high amino acids, high cortisol and growth hormone. LOW insulin
Benign mature teratomas (dermoid cysts) can be associated with malignant transformation (rarely), hypotension and fever (if they burst), anti NMDA receptor encephalitis, and ovarian torsion.
True. They are NOT associated with Addison disease.
Benign mature teratomas (dermoid cysts) can be associated with malignant transformation (rarely), hypotension and fever (if they burst), anti NMDA receptor encephalitis, and ovarian torsion.
True. They are NOT associated with Addison disease.
A coombs test only has value in assessing RBCs.
True
A coombs test only has value in assessing RBCs.
True
Prior to treating ITP with corticosteroids, a peripheral smear should be obtained to rule out leukemia or aplastic anemia.
True
In acute migraine management, what drugs would be helpful?
IV toradol, IV prochlorperazine (and a Triptan)
(NOT Promethazine which causes tissue damage)
In acute migraine management, what drugs would be helpful?
IV toradol, IV prochlorperazine (and a Triptan)
(NOT Promethazine which causes tissue damage)
In a child with suspected JIA who is stable, what is the best next step?
Consult a rheumatologist. Don’t do MRI on own.
In a child with suspected JIA who is stable, what is the best next step?
Consult a rheumatologist. Don’t do MRI on own.
To diagnose Cushing syndrome (clinical manifestations of round face, supraclavicular fat pads, abdominal striae) you need 2 of 3 first line tests to be abnormal. The tests are
24 hour urinary free cortisol, late night salivary cortisol and overnight dexamethasone suppression test
A patient with gross hematuria episodes in the setting of illness (eg strep pharyngitis) including past hematuria episodes with illness is concerning for…
What is the expected C3 and C4 level?
IgA neuropathy. C3 and c4 should be normal.
In post infectious glomerulonephritis like post strep GN, what should be the trend of C3 and C4?
C3 should be low and C4 should be normal
In a patient with repeated migraines worsened by stress from school, one option is to give non-pharmacologic interventions including
Relaxation training with bio behavioral feedback
A 17 yr old healthy male has had recurrent oral ulcers (white-gray base, erythematous halo), genital lesions (including past ones with scarring), sometimes associated with fever. He also report difficulty seeing some items at school. What dx does he have? What’s the treatment?
He has Behcet’s disease and treatment includes colchicine, steroids, azathioprine, and TNF alpha inhibitors. The illness is common in young males. The criteria requires 3 of these 6 symptoms:
Oral apthosis, genital ulcers, skin involvement (Acneiform, erythema nodosum, necrotic folliculitis), ocular involvement, neurologic signs, vascular signs.
A 4 yr old boy who has had itching, scaling, and hair loss on his R scalp for several weeks develops tactile fever and swollen, red purulent pustules in the region of alopecia. What does he have and what is the treatment?
He has tinea capitis with kerion (intense T-cell mediated hypersensitivity to the dermatophyte). He needs systemic antifungals (oral griseofulvin, terbinafine, fluconazole). There can be bacterial co-infection.
A 2wk old full term male presents to the ED with jaundice with unconjugated hyperbili of 16. He has been eating well and has normal greenish-brown stools. No evidence of hemolysis. What disease does he have and what is the treatment?
He has Crigler Najjar (Type 2) less severe version which is marked by decreased function of the bilirubin conjugation enzyme as opposed to its abscence (Type 1). He should be treated with phenobarbital.
What is the treatment for splenic sequestration?
It’s IV crystalloid given to address the hypovolemia cause by the large spleen size. Then after, a simple pRBC transfusion can help (NOT exchange). Surgical intervention is reserved only for those who fail medical mgmt (requiring continued transfusion support, persistent hypersplenism, or repeated episodes of splenic sequestration).
In any child with prolonged febrile illness and a neck mass that is not responding to antibiotics, Kawasaki disease should be considered.
yes
In sick euthyroid syndrome, what proteins are usually low?
The binding proteins: Thyroxine-binding globulin protein and transthyretin (TTR)
In sick euthyroid syndrome, what proteins are usually low?
The binding proteins: Thyroxine-binding globulin protein and transthyretin (TTR)
In sick euthyroid…
T3 is low and then T4 is low. Also, TSH is initially LOW and then can rise to well above the normal range.
However reverse T3, the inactive form of thyroid hormone, is always high.
In sick euthyroid syndrome…
T3 is low and then T4 is low. Also, TSH is initially LOW and then can rise to well above the normal range.
However reverse T3, the inactive form of thyroid hormone, is always high.
What is the biggest risk factor for ovarian torsion?
An ovarian mass including an ovarian cyst is the biggest risk factor for torsion
What is first line treatment for infantile spasms?
ACTH, corticosteroids, and vigabatrin
What is the baseline work up for tuberous sclerosis?
Brain MRI, echocardiogram and renal ultrasound because the risks are angiofibromas, retinal hematomas, cortical dysplasia, cardiac rhabdomyomas, and renal cysts
What is the recommended management when more than one magnet is swallowed? (Including magnetic beads)
If in the esophagus or stomach, then immediate endoscopy. If in the small or large bowel, then can use serial radiographs with or without total bowel clean out
What is stage 2 HTN?
Greater than the 95th percentile + 12 mmHg or once aged 13 or older, greater than or equal to 140/90
What is stage 1 HTN,
Greater than the 95th percentile to less than the 95th percentile + 12 mmHg or 130/80 to 139/89 or once aged 13 or above, from 130/80 to 139/89
What is the definition of acute severe hypertension?
A blood pressure 30mmHg or more above 95th percentile or greater than 180/120 in an adolescent
What is a complication of acute inhalant abuse?
Sudden sniffing death - surge of catecholamines leading to CV collapse.
FYI: Non-acute, more long term use can be associated with peripheral neuropathy, toxic leukoenceohalopathy, megaloblastic anemia, and subacute combined degeneration syndrome.
A 2 mo old male who presents with poor weight gain, feeding difficulties since birth, moderate head lag and poor suck reflex with birth history notable for hypotonia and undescended testicles is concerning for…
Prader-Willi syndrome. The polyhydramnios from impaired swallowing of amniotic fluid.
A 9 yr old with bilateral sensorineural hearing loss, recurrent left lateral neck swelling concerning for abscess with an enhancing tract to the left palatine tonsil is concerning for…
Branchial cleft anomaly and given the sensorineural hearing loss, needs a renal ultrasound to rule out the autosomal dominant condition, branchio-otorenal syndrome (BOR). In BOR, they usually have two of 5 features, branchial cleft anomalies, hearing loss, preauricular pits, pinna abnormalities and renal malformation.
In a patient with T1DM for years, who begins requiring less subcutaneous insulin, has fatigue, weight loss, and low-normal blood pressure (99/65) as a 16 yr old is concerning for…
adrenal insufficiency and once the patient has more than 1 autoimmune disease should be considered for autoimmune polyglandular syndrome.
A woman with history of migraine with aura who has abnormal uterine bleeding has symptomatic anemia with a Hgb 6.5. pRBC transfusion is ordered. what is the next best treatment for her?
Progestin-only oral contraceptive because she can’t have estrogen if she has migraine with aura.
If she had no hx of migraines then if she could tolerate PO, combination oral OCPs would be best and if she could not tolerate PO, then IV estrogen.
In a patient with hypertensive emergency (or hypertensive crisis) usually with BP > 30mmHg above the 95th percentile or >180/120 in an adolescent, what is the best next step in treatment and what is the goal?
Short acting anti-hypertensive (esmolol, hydralazine, labetalol, clonidine, isradipine) given oral if patient can’t take IV or if a more SEVERE complication (i.e. emergency/crisis) has occurred. The goal is GRADUAL BP reduction with BP decreased by no more than 25% of goal in first 8 hours and then normalize slowly over first 24-48hrs.
Idiopathic intracranial hypertension has been linked to several medicines including…
treatment is…
minocycline, excess vit A corticosteroids, growth hormone.
Work-up includes head imaging to rule out other causes, then LP. Treatment is diamox (acetazolamide) which can have adverse effects of metabolic acidosis, paresthesias, and metallic taste when drinking carbonated drinks. Lasix is 2nd line treatment.
When and how often does the CDC require a check of my state’s PDMP (prescription drug monitoring program) when prescribing an opioid.
Prior to every new prescription and once every 3 months for chronic prescriptions.
A teen with known T1DM is admitted with DKA. What is the most likely cause?
Insulin nonadherence. NOT increased needs in puberty.
What is the treatment for torsion of the testicular appendage? What would doppler look like in this case?
Warm compresses, NSAIDs and decreased activity. Doppler would usually be normal.
Alcohol, infections (such as Hep A), drug reactions, and autoimmune disorders often lead to a conjugated hyperbilirubinemia
Yes
For central cathethers, larger diameter cathether size relative to vein size and multiple lumen cathethers have a higher risk of thrombosis due to stagnated blood flow around the cathether.
yes. Similarly, peripherally inserted cathethers have a higher risk of thrombosis because they are in smaller veins.
A 10 yr old with 10 seconds of syncope without prodromal symptoms with immediate return to baseline thereafter while playing basketball suggests what cause and what studies would be beneficial?
Cardiac cause. Obtain EKG, Echocardiogram, and cardiac monitoring.
FYI ask about chest pain or palpitations before event. FHx sudden cardiac death under the age of 50 or a FHx congenital deafness which could be associated with long QT syndrome.
What is the inheritance pattern of Duchenne Muscular dystrophy?
X-linked recessive
In orbital cellulitis, patients under 9 yrs old, with non-frontal sinus involvement and small medial subperiosteal abscesses can be managed medically. Corticosteroids are not routinely recommended.
Yes.
A patient is considered having failed the first IVIG for KD treatment only if they have a fever after ___ hours. What should be used to manage their fevers before 36 hrs
36 hours. Use tylenol to avoid using ibuprofen when they are on aspirin.
For a patient who has failed outpatient keflex management of a cellulitis and is showing systemic signs, what is the best next step in management?
Admit them and broaden to MRSA coverage (e.g. vancomycin)
What does liver biopsy show when caused by drug (e.g. acetaminophen) injury?
Lobular inflammation with focal necrosis
What does focal nodular hyperplasia, a benign tumor of the liver more common in women aged 20-40 look like on liver biopsy?
Proliferation of hyperplastic hepatocytes surrounding a central stellate scar
By what age have most kids received 3 tetanus vaccines?
For dirty wounds (e.g. animal bite), when should a tetanus booster vaccine be given? For clean, minor wounds?
Age 6 months. Usually DTaP is given at 2 mo, 4 mo, 6 mo, 15 mo, 4-6 yrs.
Dirty wounds or major wound: When a shot has not been received in 5 years.
Clean, minor wound: Booster indicated if not received in 10 years.