Kruse: endocrine receptors and signaling pathway

Question 1

What hormones use Gs?

Answer 1

• LH
• FSH
• TSH
• Glucagon
• PTH
• PTHrP
• ACTH
• GHRH
• CRH

Question 2

What hormones use Gi

Answer 2

Somatostatin

Question 3

What hormones use Gq?

Answer 3

• TRH

- GnRH

Question 4

What hormone uses a receptor tyrosine kinase? . . give the signaling pathway

Answer 4

• Insulin

- MAP kinases, PI3 kinases, RSK

Question 5

What hormones use cytokine receptor linked kinases? . . give the pathway

Answer 5

• GH and Prolactin

- JAK, STAT, MAP kinases PI 3 kinases, IRS-1 and 2

Question 6

What uses serine kinase

Answer 6

TGF-beta . . SMADs