krebs cycle Flashcards
outline of krebs cycle
The Krebs cycle (sometimes called the citric acid cycle) consists of a series of enzyme-controlled reactions
Acetyl CoA (2C) enters the circular pathway via the link reaction
4 carbon (4C) oxaloacetate accepts the 2C acetyl fragment from acetyl CoA to form citrate (6C)
Citrate is then converted back to oxaloacetate through a series of small reactions
steps in krebs cycle
1) Oxaloacetate is regenerated in the Krebs cycle through a series of reactions
2) Decarboxylation of citrate
Releasing 2 CO2 as waste gas
3) Dehydrogenation of citrate Releasing H atoms that reduce coenzymes NAD and FAD
8H + 3NAD + FAD → 3NADH + 3H+ + FADH2
4) Substrate-level phosphorylation A phosphate is transferred from one of the intermediates to ADP, forming 1 ATP