Knee Flashcards
where is the thickest hyaline cartilage in the body found
retropatellar surface
chondrocytes
chondrocytes live in ECM in lacuna
they secrete and maintain the ECM
what properties do collagen fibres and proteoglycans have
collagen fibres have tensile strength
proteoglycans are highly hydrophilic -act like balloons to give compressive stength
cartilage healing
only healing of full thickness injuries is possible - fibrocartilage forms
this is less wear resistant and has greater friction
cartilage regeneration surgical methods
drilling/microfracture - holes drilled to induce bleeding promoting fibrocartilage formation from stem cells differentiating into chondrocytes
osteochondral autograft or allograft
mosaicplasty
MACI
mosaicplasty
- Harvest small grafts from non-weight bearing regions of knee and transplant onto affected area
MACI
membrane induced autologous chondocyte implantation - harvest healthy chondrocytes
osteochondritis dissecans
subchondral bone becomes avascular, and may progress to fragments of bone breaking away to form loose bodies
pothole on surface of bone predisposes to OA
where/who does OD commonly affect
knee - lateral side of femoral head
adolescence
treatment of OD
may heal spontaneously
lesions which are at risk of breaking off are fixed and loss fragments removed
what predisposes one to early OA of the knee
previous meniscal tears, ligament injuries, malalginment
inflammatory arthritis
patellofemoral dysfunction and instability predipose to patellofemoral OA
what OA does genu varus and valgus predipose one to
varus - medial
valgus - lateral
who would receive an osteotomy to treat OA
younger patients with isolated medial compartment OA - particularly in varus knee - shift the load to the lateral compartment
heavy manual workers
results of osteotomy
unpredictable
benefit lasts around 7-10 years
can affect results of later TKR
when is knee replacement considered (OA)
patient with substantial pain and disability where conservative management is no longer effective
partial or total
results of knee replacement
dissapointing results for OA
younger patients have poorer outcomes
PKR poorer results than TKR (80% satisfaction, 20% ongoing pain)
when is unicompartmental knee replacement considered
potential treatment for patients with isolated OA
particularly younger patients
risks of KR surgery
infection, thrombosis
often unexplained knee pain after TKR
likely failure and revision surgery in younger patients
if the knee examination is difficult due to pain, but is thought to be significant what will be performed
MRI
when do meniscal tears classically occur
twisting force on loaded knee or when getting up from squatting
who do meniscal tears usually occur in
sporting injuries in younger patients
meniscal injury
twsting force/getting up from squatting
pain localises to medial/lateral joint line
effusion develops (inc synovial fluid)
pain and mechanical symptoms - catching/locking
what clinical examination will be performed in acute meniscal tear
steinmann’s test - pain on tibial rotation localising to affected compartment
what is found in the knee joint in meniscal tear
effusion - increased synovial fluid
what will confirm clinical suspicion of a meniscal tear
MRI
true knee locking
- mechanical block to full extension caused by torn meniscus flipping over and becoming stuck in joint line
- may require partial meniscectomy to unlock knee and prevent further damage
- can perform heel height test if suspected
what is true knee locking a clinical sign of
meniscal tear
- can occur without locking however
pseudlocking
can occur in patients with OA etc that describe their knee can temporarily become stuck when straightening the joint
are lateral or medial meniscal tears more common
medial as it is fixed (lateral is mobile)
types of meniscal tear