Klebsiella Pneumniae

Question 1

Klebsiella clinical syndrome

Answer 1

Primary pneumonia when underlying medical problems are present (alcoholism, diabetes, lung disease)
-"red current jelly" sputum 
UT and wound infections
bacteremia and meningitis 
diarrhea by enterotoxigenic strains

Question 2

Klebsiella Virulence factor

Answer 2

Capsule is main virulence factor

• reduced phagocytosis
• reduced complement susceptibility
• capsule production also help identify K. pneumoniae based on mucoid colony morphology