Kinetics of Lactate Dehydrogenase Flashcards
1
Q
What does lactate dehydrogenase catalyse under anaerobic conditions ?
A
The reduction of pyruvated to lactate
2
Q
What is the structure of lactate ?
A
Tetramer
3
Q
What are the two types of LDH subunits ?
A
M and H
4
Q
What do the LDH subunits have the same and different ?
A
They have similar relative molecular mass but different amino acid composition and differing kinetic properties
5
Q
How many tetrameric isoenzymes result from two different subunits ?
A
5
6
Q
What are LDH1 and LDH2 ?
A
Predominant components of heart LDH
7
Q
What is LDH 3 ?
A
Principal component of LDH from lymphatic tissue
8
Q
What is LDH4 and LDH5 ?
A
Predominant components of skeletal muscle and liver LDH
