Kinetics BrainScrape CYPs Flashcards by Casey Jones | Brainscape

Q

Amiodarone

A

Inhibitor of CYP2C9

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Q

Azoantifungals

A

Substrate CYP3A4

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Q

Barbiturates

A

Inducer of CYP2C19

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Q

Benzos except lorazepam/oxazepam

A

Substrate CYP3A4

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Q

Carbamazepine

A

Inducer of CYP 3A4

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Q

Caffeine

A

Substrate of CYP1A2

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Q

Carbamazepine

A

Inducer of CYP2C9

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Q

CCBs

A

Substrate CYP3A4

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Q

Charbroiled meat

A

Inducer of CYP1A2

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Q

Chlorpromazine (antipsychotics)

A

Substrate of CYP2D6

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Q

Chlorzoaxazone

A

Substrate of CYP2E1

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Q

Clarithromycin

A

Inhibitor of CYP3A4

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Q

Cimetidine

A

Inhibitor of CYP3A4, 1A2, 2C9

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Q

Clozapine

A

Substrate of CYP1A2

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Q

Cigarette smoke

A

Inducer of CYP1A2, CYP2E1

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Q

Cipro

A

Inhibitor of CYP1A2

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Q

Bisoprolol

A

Substrate of CYP2D6

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Q

Codeine (opioid analgesics)

A

Substrate of CYP2D6

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Q

Cruciferous vegetables

A

Inducer of CYP1A2

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Q

Dexamthasone

A

Inducer of CYP 3A4, 2C9

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Q

Diazepam

A

Substrate of CYP2C19

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Q

Diltiazem

A

Inhibitor of CYP1A2

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Q

Disulfram

A

Inhibitor of CYP2E1

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Q

Ecainide (antiarrhthmics)

A

Substrate of CYP2D6

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Q

Efavirenz

A

Inducer of CYP 3A4

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Q

Enflurance

A

Substrate of CYP2E1

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Q

Enoxacin

A

Inhibitor of CYP1A2

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Q

Erythryomycin

A

Inhibitor of CYP3A4

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Q

Ethanol

A

Inducer and Substrate of CYP2E1

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Q

Fluoxetime (most SSRIs)

A

Substrate of CYP2D6

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Q

Fluconazole

A

Inhibitor of CYP2C9

Q

Fluoxetine

A

Inhibitor of CYP2D6, 2C19

Q

Fluvastatin

A

Substrate of CYP2C9

Q

Fluvoxamine

A

Most potent Inhibitor of CYP1A2, also inhibitor of CYP2C9, 2C19

Q

Garlic

A

Inhibitor of CYP2E1

Q

Glibenclamide

A

Substrate of CYP2C9

Q

Glimipiride

A

Substrate of CYP2C9

Q

Glipizide

A

Substrate of CYP2C9

Q

Grapefruit Juice

A

Inhibitor of CYP3A4

Q

Halothane

A

Substrate of CYP2E1

Q

HMG-CoA Reductase Inhibitor except Pravastatin

A

Substrate CYP3A4

Q

Isoflurane

A

Substrate of CYP2E1

Q

Isoniazid

A

Substrate of CYP2E1

Q

Itraconazole

A

Inhibitor of CYP2C9

Q

Isoniazid

A

Inducer of CYP2E1

Q

Ketoconazole

A

Inhibitor of CYP3A4

Q

Macrolide antibiotics except Azithromycin

A

Substrate CYP3A4

Q

Methoxyflurane

A

Substrate of CYP2E1

Q

Metronidazole

A

Inhibitor of CYP2C9

Q

Nevirapine

A

Inducer of CYP 3A4

Q

Norfloxacin

A

Inhibitor of CYP1A2

Q

NSAIDs

A

Substrate of CYP2C9

Q

Olanzapine

A

Substrate of CYP1A2

Q

Omeprazole

A

Substrate of CYP2C19 and Inhibitor of CYP2C19

inducer of CYP1A2

Q

Paroxetine

A

Inhibitor of CYP2D6

Q

Phenobarb

A

Inducer of CYP3A4, 1A2, 2C9,

Q

Phenytoin

A

Inducer of CYP3A4, 2C9,

Q

Primidone

A

Inducer of CYP 3A4, 1A2,

Q

Quinidine

A

Inhibitor of CYP2D6

Q

R-warfarin

A

Substrate of CYP1A2

Q

Rifabutin

A

Inducer of CYP 3A4

Q

Rifampin

A

Inducer of CYP 3A4, 1A2, 2C9, 2C19

Q

Riluzole

A

Substrate of CYP1A2

Q

Ritonavir

A

Inhibitor of CYP3A4, 1A2, 2E1

Q

Ropivacaine

A

Substrate of CYP1A2

Q

S-mephenytoin

A

Substrate of CYP2C19

Q

S-warfarin

A

Substrate of CYP2C9

Q

Sevoflurane

A

Substrate of CYP2E1

Q

SJW

A

Inducer of CYP3A4, 2E1, 2C9

Q

Steroids (BC, corticosteroids)

A

Substrate CYP3A4

Q

Sulfonamides

A

Inhibitor of CYP2C9

Q

Tacrine

A

Substrate of CYP1A2

Q

Theophylline

A

Substrate of CYP1A2

Q

Tolbutamide

A

Substrate of CYP2C9

Q

Tricyclic antidepressants

A

Substrate of CYP2D6

Q

Troleandomycin

A

Inhibitor of CYP3A4

Q

zileuton

A

Inhibitor of CYP1A2