Kinetics

Question 1

First order kinetics =

Answer 1

k[S]¹ or k[S]

Question 2

Answer 2

First order kinetics

Question 3

Answer 3

Second Order Kinetics

Question 4

Second Order Kinetic =

Answer 4

k[S]² or k[S_A][S_B​]

Question 5

Zero Order Kinetics =

Answer 5

k[S]⁰ or k

Question 6

Answer 6

Zero Order Kinetic

Question 7

At equilibrium

Answer 7

the forward rate = the reverese rate

or

k₁[S] = k_-1[P]

Question 8

K_A interpertations

Answer 8

K_A is the association constant

K_A > 1 forming mostly products

K_A < 1 forming mostly substrate

K_A = @ equilibrium

Question 9

K_D interpertations

Answer 9

K_D is the dissociation constant

K_D > 1 forming substrate

K_D < 1 forming product

K_D = 1 @ equilibrium

Question 10

K_m

Answer 10

Michaelis Constant [S] where reaction rate is half maximal or half the active sites are full

Question 11

V_max

Answer 11

Maximum velocity or the maximum rate possible for a given concentration of enzyme. Reached when enzyme is full saturated [E*S]=[E]_T

v_max = k_cat[E]_T

Question 12

k_cat, k₂

Answer 12

Turnover number or number of substrate molecules converted per active site per time (first order rate constant)

Question 13

K_s, K_-1

Answer 13

a dissociation constant for substarate binding

Question 14

k_cat/K_m

Answer 14

Specificity constant or the measure of enzyme performance by predicting fate of E*S, product or back to E+S

Question 15

What is the rate determining step for enzyme kinetics?

Answer 15

k₂ ; E*S → E + P

Question 16

Michaelis-Menten Equation

Answer 16

v₀ = v_max/ (K_m + [S])