Kinetics Flashcards
1
Q
Km =
A
[E][S]/[ES]
In the graph, the X when Vmax/2.
2
Q
Kcat=
A
=Vmax/[E]
Rate of ES–> EP
3
Q
Vmax
A
Kcat*[E]
4
Q
V=
A
(Vmax*[S])/(Km+[S])
5
Q
Exergonic G
A
Delta G
6
Q
Endergonic G
A
Delta G > 0
7
Q
1/v=
A
(Km/(Vmax[S]) + (1/Vmax)
8
Q
Intercepts of Lineweaver-Burke plot
A
X: -1/Km
Y: 1/Vmax
9
Q
Slope of line weaver burk plot
A
Km/Vmax
10
Q
Allosteric V type inhibitor
A
Reduces Vmax, does not change Km
11
Q
Allosteric K type inhibitor
A
Km decreased, Vmax stays the same
12
Q
Competitive inhibitor
A
Vmax is the same
Km increased
13
Q
Noncompetitive inhibitor
A
Vmax decreased
Km Same
