kidneys/urinary Flashcards
4 fxns of renal system
maintain volume and composition of body fluids WNL
REgulate vit D activation
regulate blood pressure thru renin angiotension-aldosterone
Regulate RBC production thru production of erthryopoietin
ADH
maintains fluid balance
relaces in a fall in blood volume, sympathetic stimulation, or Rise in NA+ levels
chloride regulation
- ion (reabsorbed in loop of henle)
helps maintain electrical neutrality w/ movement of cations across cell membrane
potassium regulation
fxn of nervous system, muscle, cell membranes
Aldosterone
stimulates the sodium-potassium exchange pump
released when too high K+ levels sympathetic stimulation or angiotension II
Hydrochlorothiazide indications
for newly HTN pts
therapy for edema w/ HF, liver, renal disease
Hydrochlorothiazide action
reabsorbs sodium and chloride in distal renal tubules
for excretion of na,cl, h2o inkidneys
Hydrochlorothiazide AD
dizz, vertigo, orthostatic hypoTN, nasuesa,v, muscle cramps, dry mouth, diarrhea, polyuria, spams
Hydrochlorothiazide Contra
allergy to this drug or sulfonamide f&e imbalance/liver renal diease bipolar disorder hyperthyroidism diabetes/ glucose intolerance
Hydrochlorothiazide d/d
combied with cholestyramine or colestipol
digoxin toxiticy b/c K+ changes
diabetc meds
lithium toxicity
Furosemide indication
in loop of henle) trt edema with CHF, acute pulmonary edema, HTN
Furosemide actions
reabsorption of NA+ and CL from distal renal tublues/loop of hen
Furosemide AE
dizz,vertigo, paethesias, orthostic HypoTN, urticaria, hyperglycemia, urine bladder spams
hypokalcemia, alkalosis, hypocalemia
f&e imbalance
Furosemide contra
allergy, electrolyte imbalance, renal failure, hepatic coma, lupus, diabetes
Furosemide d/d
anticoags ^ risk with ototoxicity
NSAID, ibprofen
Acetazolamide indication
trt open angle glaucoma> reliefs interocular pressure
CHF/ drug induced edema
Acetazolamide actions
inhibits carbonic anhydrase which decrease aqueous humor, intraocular pressure
Acetazolamide AE
disturbance of acid base balance, electrolyte balance
metabolic acidosis
hypokalcemia
confusion, drowzie, kid stones, wt loss, paresthesais extremities
Acetazolamide contra
chornic noncongestive glaucoma
F&E imbalance
renal/hepatic disease
respiratory acidosis, COPD