Kidneys Flashcards

1
Q

What hormones are produced in the kidneys?

A

Erythropoietin (EPO)
Renin-Aldosterone-Angiotensin System
1, 25-dihydroxyvitamin D3

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2
Q

What is the site of synthesis for EPO?

A

Kidney

Fetus-Liver

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3
Q

What is the function of EPO?

A

Stimulate development of RBC’s

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4
Q

What controls the secretion of EPO?

A

Endorphins
Substance P
Oxytocin
Thyroxine

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5
Q

The renin angiotensin aldosterone system regulates?

A

BP

Fluid Balance

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6
Q

The renin-angiotensin-aldosterone system is activated if there is a loss of?

A

Blood Volume

BP

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7
Q

What signals the juxtaglomerular cells to release renin?

A

Macula Densa Cells

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8
Q

Macula densa senses a decrease in blood pressure which causes a decrease in?

A

Glomerular Filtration Rate (GFR)

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9
Q

What is the function of macula densa cells?

A

Stimulates renin release in juxtaglomerular cells

Osmolarity of plasma

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10
Q

What cells in the kidney release renin into circulation?

A

Juxtaglomerular Cells

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11
Q

What causes blood vessels to constrict?

A

Angiotensin II

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12
Q

Angiotensin II stimulates the release of aldosterone from the?

A

Adrenal Cortex

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13
Q

Aldosterone increases reabsorption of sodium and water which increases?

A

BP

Fluid Volume

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14
Q

The renin-angiotensin-aldosterone system stimulates the release of?

A

Norepinepherine

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15
Q

Renin-angiotensin-aldosterone system increases vasoconstriction of blood vessels which increases BP when the pressure is too?

A

Low

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16
Q

The kidney and it’s hormones brings BP up to?

A

Normal

17
Q

What hormone regulates the amount of water excreted by the kidneys?

A

Antidiuretic Hormone (ADH)

18
Q

What monitors either the amount of volume of blood going through the hypothalamus or the concentration of water in the blood?

A

Hypothalamus

19
Q

Aldosterone is secreted from what part of the adrenal gland?

A

Zona Glomerulosa

20
Q

What is the primary target of aldosterone?

A

Kidneys

21
Q

Aldosterone is important for what?

A

Sodium and Water Absorption

22
Q

PTH regulates what?

A

Calcium and Phosphate

23
Q

What is the site of synthesis for atrial natriuretic peptide?

A

Atrium of the heart

24
Q

ANP stimulates renal excretion of sodium by decreasing secretion of?

A

Angiotensin II

25
Q

What’s the primary function of ADH?

A

Increase Renal Reabsorption of Water

26
Q

What disease has a decreased output of ADH?

A

Central Diabetes Insipidus

27
Q

Central diabetes insipidus has what symptoms?

A

Excessive Urine Output and Thirst

28
Q

Central diabetes insipidus has increased aldosterone after?

A

Compensation

29
Q

What is the reason for increased aldosterone after compensation?

A

BP drops and body tries to restore it to normal

30
Q

What are the physical characteristics of central diabetes insipidus?

A

Polyuria
Dilute Urine
Hypotension
Increased Plasma Concentration

31
Q

What disease has a decreased sensitivity to ADH but and increased secretion of ADH?

A

Nephrogenic Diabetes Insipidus

32
Q

Excessive release of ADH causes what disease?

A

Syndrome of Inappropriate ADH secretion

33
Q

Syndrome of inappropriate ADH secretion causes fluid overload in patients which can lead to?

A

Strokes
Head Trauma
Brian Tumors