Kidneys Flashcards
Diuretics
- doesnt want reabsorption so there
• A diuretic is a type of chemical that causes the kidneys to make more urine
be move pee
• Diuretics cause the body to get rid of extra fluid and salt (can cause dehydration)
• They are used to treat high blood pressure and water retention
• present in caffeine & alcohol
Osmoreceptors and the hypothalamus
• Osmoreceptors are cells that are sensitive to osmotic pressure
• Most osmoreceptors are in the hypothalamus → part of the brain that regulates hunger
thirst
pressure
body temperature
wants more t20 reaboratio
• Osmotic pressure is the force generated as water moves by osmosis
•
High osmotic pressure = “more salty blood” = low blood volume and pressure
a pee is more yellow
*ADH is in
• Low osmotic pressure = “less salty blood” = high blood volume and pressure •
collecting ADH (antidiuretic hormone) function
Wants less H20
ducts
• ADH is produced in the hypothalamus but released by the pituitary gland
reabsoption & pee is
less yellow
• ADH increases water reabsorption in the collecting ducts of the nephron in the kidneys
• ADH released in response to dehydration (detected as “salty” blood by osmoreceptors)
• High osmotic pressure (salty blood) → More ADH → More water retention
• Low osmotic pressure (less salty blood) → Less ADH → Less water retention
Mechanism of Action
• ADH binds to receptors in the collecting ducts of the nephron
• Result: Increased water reabsorption in the collecting ducts
• Increased blood volume and pressure
• Decreased urine volume (more yellow)
Hypothalamus creates
teclings of thirst.
Hypothalamus detects
higher concentration
of solutes in blood.
Water level drops
below normal range.
Posterior pituitary
releases more ADH.
Homeostasis:
Water level in blood
The person drinks
water
ADH stim-
ulates kidneys
to reabsorb
more water
Kidneys reabsorb
less water.
Water level rises
above normal range.
Pituitary releases
less ADH.
Hypothalamus
detects low
solute concentration.