Kidney/LUT Flashcards
First sign tubule cell dysfunction
inability to concetrate urine
Fixed specific gravity
chronic renal failure; cannot concentrate or dilute urine
Negative urine bilirubin + trace urobilinogen
normal urine
Positive urine bilirubin, absent urobilinogen
obstructive jaundice
Positive urine bilirubin + increased urobilinogen
hepatitis
Negative urine nitrite + positive urine leukocyte esterase
urinary tract infection
Sterile pyuria
positive urine leukocyte esterase but negative standard culture; TB, C. trachomatis
Prerenal azotemia
increase BUN and creatinine; decrease renal blood flow (.eg., heart failure, hypovolemia)
Renal azotemia
increase BUN and creatinine due to intrinsic renal disease (acute tubular necrosis)
Postrenal azotemia
increase BUN and creatinine due to obstruction to urine flow
Serum BUN:creatinine ratio
15:1 (prerenal or postrenal azotemia)
BUN 80mg/dL:creatinine 8mg/dL
ratio 10:1 indicates renal failure
BUN 80mg/dL:creatinine 2mg/dL
ratio 40:1 indicates prerenal azotemia or postrenal azotemia
Creatinine clearance
measures GFR
Proteinuria
important sign of renal dysfunction