kidney injury Flashcards
most common cause of AKI
sepsis
Stage 4 CKD eGFR
15-29
Stage 5 eGFR
<15
prerenal causes of AKI
hypotension, hypovolemia, sepsis
intrarenal causes of kidney damage
drug toxicity, myoglobin, radiocontrast, immune attack, infections
Postrenal causes of AKI
obstruction due to kidney stones, kidney or bladder cancer
secondary kidney injury occurs in _____
hypertension an diabetes
Main difference between stage 5 CKD and ESRD
ESRD requires dialysis or transplant to keep patient alive
Most common cause of CKD
Diabetes
stage 3 CKD eGFR
30-59 (most people diagnosed at this stage)
Causes of CKD
Loss of nephrons due to diseases such as diabetes and hypertension.
Nephron workload
increases with disease and causes nephrons to die
death pathway of nephrons
gomerulosclerosis
Major manifestations of ESRD
Hypertension, metabolic acidosis, Anemia
Mineral and bone disorder (CKD-MBD
What causes CKD-MBD
calcium and phosphate abnormalities