Kidney function Flashcards
Two main parts of the kidney
Renal cortex
Renal medulla
Parts of the nephron
Glomerulus
Tubules
Which is the functional part of the kidney?
The nephron
Acronym AEIOU
Acidosis Electrolytes Intoxication Overload Uremia
What is the glomerulus?
A ball of capillaries in a sac called Bowman’s Capsule.
Parts of the tubular system
- Proximal convoluted tubule
- Loop of Henle
- Distal convoluted tubule
- Collecting tubule
Functions of the kidney in maintaining homeostasis
- Remove water and waste
- Maintain electrolyte balance
- Control BP
- Make hormones
- Maintain pH
Hormones/enzymes made by kidneys
- Erythropoietin
- Calcitriol
- Renin
What does erythropoietin do?
Tells bone marrow to make RBCs
What does calcitriol do?
Allow gut to absorb calcium from food
What does renin do?
Helps control BP
Seven major electrolytes
- Sodium
- Chloride
- Calcium
- Bicarb
- Magnesium
- Phosphate
- Potassium
Two ways kidneys control BP
- Retain or release water
2. Use renin to form angiotensin, which holds onto salt and water and constricts vessels
Symptoms of metabolic acidosis
- Weakness & fatigue
- Rapid breathing
- Racing heartbeat
- Headache
- Confusion
Types of kidney failure
- Acute Kidney Failure (AKI)
2. Chronic Kidney Disease
Acute Kidney Injury (AKI)
Sudden severe loss of kidney function
Causes of AKI
- Dehydration
- Toxins
- Sepsis
Chronic Kidney Disease
How to slow progression of CKD
- Keep BG in target range
- Keep BP in target range
- Avoid NSAIDs
- Quit smoking
- Ask doctor for protecting kidneys from X Rays or CT scans
Causes of Kidney Failure
- Diabetes
- High BP
- Glomerular disease
Two main types of diabetes
Type 1
Type 2
Two types of high blood pressure
- Primary or essential hypertension
2. Secondary hypertension
Diseases of glomeruli
- Glomerulonephritis
2. Glomerulosclerosis
What is glomerulosclerosis?
Hardening of the glomeruli
What is glomerulonephritis?
Inflammation of the glomeruli
What is Polycystic Kidney Disease (PKD)?
A genetic disease that causes fluid-filler cysts that can grow in the kidneys and sometimes liver.
Hypernatremia
High sodium in the blood
Causes of hypernatremia
- Dehydration
- Water and salt both lost
Symptoms of hypernatremia
- Intense thirst
- Confusion
- Seizures
- Death
Hyponatremia
Low salt in the blood
Symptoms of hyponatremia
- Muscle cramping
- Restlessness
- Confusion
- Headache
- Fatal brain swelling
Hyperkalemia
High potassium
Causes of hyperkalemia
- Pt eating a lot of high-potassium foods
- Severe blood loss
- Crush injuries
- Trauma
- Hemolysis
- Missed dialysis treatments
Hypokalemia
Low potassium
Causes of hypokalemia
- Some kidney function but on dialysis
- Vomiting/diarrhea
- Does not eat enough potassium in diet
- Dialysis removes too much potassium
Symptoms of hyperkalemia
- Altered heart rhythm
- Weakness
- Skipped heartbeats or asystole
Symptoms of hypokalemia
- Tingling/numbness
- Fatigue
- Weak muscles
- Muscle damage
- Fainting
- Changes in heart rhythms
Hypercalcemia
Too much calcium
Symptoms of hypercalcemia
- Fatigue
- Vomiting
- Weakness
- Muscle twitches
- Confusion