Keywords Flashcards

1
Q

What is The mode of action of antimetabolites is

A

antimetabolites inhibit the replication or the repair of DNA either by the direct inhibition of enzymes needed for DNA replication or by the incorporation of the antimetabolite (or a compound derived from the antimetabolite) directly into the DNA.

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2
Q

Cisplatin is:

A

DNA damaging drugs

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3
Q

Desensitisation

A

y, desensitization is a treatment or process that diminishes emotional responsiveness to a negative, aversive or positive stimulus after repeated exposure to it.

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4
Q

Sensitisation

A

is a non-associative learning process in which repeated administration of a stimulus results in the progressive amplification of a response. Sensitization often is characterized by an enhancement of response to a whole class of stimuli in addition to the one that is repeated.

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5
Q

Biotransformation

A

Once inside us, they are transported to the liver, where enzymes start the process of breaking them down, known as biotransformation,

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6
Q

Bioavability

A

he proportion of a drug or other substance which enters the circulation when introduced into the body and so is able to have an active effect.

For example with intramusclue administraion bioadvibility is 100%

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7
Q

Agonists

A

a substance which initiates a physiological response when combined with a receptor

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8
Q

Antagonists

A

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

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