Keywords Flashcards
What is The mode of action of antimetabolites is
antimetabolites inhibit the replication or the repair of DNA either by the direct inhibition of enzymes needed for DNA replication or by the incorporation of the antimetabolite (or a compound derived from the antimetabolite) directly into the DNA.
Cisplatin is:
DNA damaging drugs
Desensitisation
y, desensitization is a treatment or process that diminishes emotional responsiveness to a negative, aversive or positive stimulus after repeated exposure to it.
Sensitisation
is a non-associative learning process in which repeated administration of a stimulus results in the progressive amplification of a response. Sensitization often is characterized by an enhancement of response to a whole class of stimuli in addition to the one that is repeated.
Biotransformation
Once inside us, they are transported to the liver, where enzymes start the process of breaking them down, known as biotransformation,
Bioavability
he proportion of a drug or other substance which enters the circulation when introduced into the body and so is able to have an active effect.
For example with intramusclue administraion bioadvibility is 100%
Agonists
a substance which initiates a physiological response when combined with a receptor
Antagonists
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.