Keys Flashcards
Is basal cell carcinoma inherited?
(1) Gorlin-Goltz’s syndrome – AD - BCC, jaw cysts, minor skeletal changes (fifth phakomatosis)
(2) Bazex’s syndrome – XL - BCC, congenital hypotrichosis, follicular atrophoderma
(3) Xeroderma pigmentosa – AR - abnormal UV repair
List the causes of lid retraction in TED.
(1) Humorally-induced overaction of Müller muscle (2) Fibrotic contracture of LPS
(3) Secondary overaction of LPS-SR complex to counter fibrotic IR
(4) Proptosis
What are the systemic associations of limbal dermoids?
(1) Goldenhar Syndrome
(2) Linear Sebaceous Naevus Syndrome (3) Treacher-Collins Syndrome
List conditions where proptosis is exacerbated by valsalva.
Orbital varices; cap haemangioma;
List conditions associated with bilateral exophthalmos.
TED; CCF; Cavernous sinus thrombosis; Wegener’s; Lymphoma; Sarcoid; Craniosynostosis; IOIS;
List conditions causing enophthalmos.
Sclerosing tumours (metastatic breast ca), orbital varix, orbital wall fractures
How do you differentiate clinically and radiologically between the two main lacrimal gland tumours?
Pleomorphic Adenoma – Benign; painless, single/solid bosselated surface; (incomplete excision bad); bone remodelling
Adenoid Cystic Ca. – no intact capsule; “swiss cheese”; faster onset; painful; Ca++; bone erosion; amorphous post extension
How are nasolacrimal duct obstructions diagnosed in children?
NB. Must exclude congenital glaucoma
Epiphora; increased tear lake; mucopurulent discharge in absence of URTI; dye disappearance test
List clinical or radiological features of silent sinus syndrome.
CLINICAL: Spontaneous enophthalmos & hypoglobus. Eyelid retraction/lid lag/lagophthalmos, Deepening superior orbital sulcus, Normal vision is unaffected.
RADIOLOGICAL: partial or complete maxillary opacification, reduction of maxillary sinus volume & orbital volume enlargement. Inferior bowing of maxillary roof
How do you classify ptosis?
NB. Must examine pupils + EOM
- Neurogenic (3rd; Horners; MGJWS, blepharophimosis ptosis epicanthus inversus synd FOXL2)
- Myogenic (MDdystro; Simple Congenital, CPEO; Neuromuscular: MG, botox)
- Aponeurotic (involutional; post surg)
- Mechanical (tumours; dermatochalasis; oedema; orbital lesions; scarring)
Compare congenital myogenic to acquired aponeurotic ptosis.
(1) ULC: Weak/absent crease in normal position (congenital) vs. Higher than normal (acquired)
(2) Levator Function: Reduced (congenital) vs. Normal (acquired)
(3) Down gaze: Eyelid lag (congenital) vs. Eyelid drop (acquired)
What are the causes for pseudo-ptosis?
Hypoglobus/tropia, dermatochalasis, Enophthalmosis (phthisis/wall #); Contralat. proptosis; Contralat. UL retraction (TED)
How do you classify acquired ectropion?
- Paralytic - 2° CN VII palsy causing orbicularis weakness
- Mechanical - 2° visible/palpable mass i.e. tumour/cyst/oedema
- Cicatricial – scarring vertically shortens the anterior lamella
- Involutional - age-related lid laxity
What systemic diseases can capillary haemangiomas cause?
Kasahach-Merrit Syndrome (platelet consuption); High output CCF; Laryngeal obstruction
List three organisms that can cause preseptal cellulitis.
- Staphylococcus aureus
- Streptococcus spp (Strep. pyogenes, Strep pneumoniae)
- Haemophilus influenzae type b