Key Terms Test 2 Flashcards
anemia
a condition characterized by a lower than normal hemoglobin concentration
erythrocyte
red blood cell
erythropoiesis
production of erythrocytes
erythropoietin
- a hormone produced primarily by the kidneys
- erythropoietin levels increase if the kidneys detect low levels of O2
hematocrit (HCT)
- measures the mass/weight of the RBC (how big it is)
- generally 3x the HGB
hemoglobin (HGB)
- main component of RBCs
- acts as the vehicle in transportation of O2
red blood cell (RBC)
principle means of delivering oxygen to body tissues
reticulocytes
immature RBCs
gas exchange
the process by which oxygen is transported TO cells and carbon dioxide is transported FROM cells
ischemia
inadequate blood supply to an organ/part of the body
hypoxia
low levels of O2 in body tissues or cells
anoxia
no oxygen to cell or tissue
diffusion
movement of a substance from high concentration to low concentration
air trapping
incomplete emptying of alveoli during expiration due to loss of lung tissue elasticity (emphysema), bronchospasm (asthma), or airway obstruction
Alpha1-antitrypsin deficiency
- genetic disorder resulting from deficiency of alpha1-antitrypsin, a protective agent for the lung
- Increases the patient’s risk for developing panacinar emphysema even in the absence of smoking
asthma
- a heterogenous disease usually characterized by chronic airway inflammation
- Defined by history of symptoms such as wheeze, shortness of breath, chest tightness, and cough that vary over time and in intensity
bronchiectasis
- chronic, irreversible dilation of the bronchi and bronchioles that results from the destruction of muscles and elastic connective tissue
- Dilated airways become saccular and are a medium for chronic infection
chest percussion
manually cupping hands over the chest wall and using vibration to mobilize secretions by mechanically dislodging viscous or adherent secretions in the lungs
chest physiotherapy (CPT)
- therapy used to remove bronchial secretions, improve ventilation, and increase the efficiency of the respiratory muscles
- Types include postural drainage, chest percussion and vibration, and breathing retraining
chronic bronchitis
a disease of the airways defined as the presence of cough and sputum production for at least a combined total of 3 months in each of 2 consecutive years
desaturate
a precipitous drop in the saturation of hemoglobin with oxygen
dry-powder inhaler (DPI)
a compact, portable inspiratory flow-driven inhaler that delivers dry powder medications into the patient’s lungs
emphysema
a disease of the airways characterized by destruction of the walls of overdistended alveoli
flutter valve
- portable handheld mucus clearance device consisting of a tube with an oscillating ball inside
- Upon expiration, high-frequency oscillations facilitate mucous expectoration
fraction of inspired oxygen (FiO2)
concentration of oxygen delivered (e.g. 1.0 equals to 100% oxygen)
hypoxemia
decrease in arterial oxygen tension in the blood
polycythemia
- increase in the red blood cell concentration in the blood
- In COPD, the body attempts to improve oxygen-carrying capacity by producing increasing amounts of red blood cells
postural drainage
positioning the patient to allow drainage from all lobes of the lungs and airways
pressurized metered-dose inhaler (pMDI)
a compact, portable patient activated pressurized medication canister that provides aerosolized medication that the patient inhales into the lungs
small-volume nebulizer (SVN)
a handheld generator-driven medication delivery system that provides aerosolized liquid medication that the patient inhales into the lungs
spirometry
- pulmonary function tests that measure specific lung volumes and rates
- May be measured before and after bronchodilator administration
vibration
a type of massage given by quickly tapping the chest with the fingertips or alternating the fingers in a rhythmic manner, or by using a mechanical device to assist in mobilizing lung secretions
anthropometrics
height and weight
B cells in the pancreas
secretes insulin, the body mistakenly destroys these cells in type 1 diabetes
central obesity
excess weight that develops over time around the center of the body, also called visceral fat
counterregulatory hormones
- raise glucose: glucagon, cortisol
- Increase with stress
diabetes
a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both
Type 1 diabetes
a metabolic disorder characterized by an absence of insulin production and secretion from autoimmune destruction of the beta cells of the islets of Langerhans in the pancreas (formerly: insulin-dependent diabetes, or juvenile diabetes)
type 2 diabetes
a metabolic disorder characterized by the relative deficiency of insulin production and a decreased insulin action and increased insulin resistance (formerly: non–insulin-dependent diabetes, or adult-onset diabetes)
diabetes distress
when a person feels frustrated, defeated, or overwhelmed by diabetes
diabetic ketoacidosis (DKA)
- a metabolic derangement, most commonly occurring in type 1 diabetes, that results from a deficiency of insulin
- Highly acidic ketone bodies are formed, resulting in acidosis
polyphagia
excessive eating
polydipsia
excessive water drinking
polyuria
excessive urination
fasting plasma glucose (FPG)
blood glucose determination obtained in the laboratory after fasting for 8 hours
gestational diabetes
any degree of glucose intolerance with its onset during pregnancy
glucagon
counterregulatory hormone that suppresses insulin and increases blood sugar
glucose tolerance test (GTT)
a lab test to check how your body moves sugar from the blood into tissues like muscle and fat
glycated hemoglobin (A1C)
a measure of glucose control that is a result of glucose molecule attaching to hemoglobin for the life of the red blood cell (120 days)
Synonyms: glycosylated hemoglobin, HgbA1C, A1C
glycemic index
the amount a given food increases the blood glucose level compared with an equivalent amount of glucose
glycogen
how the body stores glucose
gluconeogenesis
the formation of glucose by the liver to form noncarbohydrate sources, such as amino acids and the glycerol portion of fats
glycogenolysis
the breakdown of glycogen
hyperglycemia
elevated blood glucose level
hyperglycemic hyperosmolar syndrome (HHS)
a metabolic disorder, most commonly of type 2 diabetes resulting from a relative insulin deficiency initiated by an illness that raises the demand for insulin
hypoglycemia
low blood glucose level
Impaired fasting glucose (IFG) or impaired glucose tolerance (IGT)
a metabolic stage intermediate between normal glucose homeostasis and diabetes; referred to as prediabetes
insulin
- a hormone secreted by the beta cells of the islets of Langerhans of the pancreas that is necessary for the metabolism of carbohydrates, proteins, and fats
- Deficiency results in diabetes
rapid acting insulin
short acting insulin
intermediate acting insulin
long acting insulin
premixed inslin
insulin resistance
ketone
a highly acidic substance formed when the liver breaks down free fatty acids in the absence of insulin
lipohypertrophy
medical nutrition therapy (MNT)
nutritional therapy prescribed for management of diabetes that usually is given by a registered dietitian
microalbuminuria
myplate.gov
nephropathy
- a long-term complication of diabetes in which the kidney cells are damaged
- Characterized by microalbuminuria in early stages and progressing to end-stage kidney disease
neuropathy
a long-term complication of diabetes resulting from damage to the nerve cell
pharmacologic agents
oral hypogycemic agents
biguanide class
thiazolidinedione
sulfonylureas
incretin agents
SGLT-2 inhibitors
basal insulin
mealtime insulin
mixed preparations
statins
prediabetes
- impaired glucose metabolism in which blood glucose concentrations fall between normal levels and those considered diagnostic for diabetes
- includes impaired fasting glucose and impaired glucose tolerance, not clinical entities in their own right but risk factors for future diabetes and cardiovascular disease
retinopathy
a condition that occurs when the small blood vessels that nourish the retina in the eye are damaged
self-monitoring of blood glucose
a method of capillary blood glucose testing