Key Terms

Question 1

DRUG effects, sometimes called SIDE effects , that are NOT the desired therapeutic effects ; may be unpleasant or even DANGEROUS

Answer 1

ADVERSE effects

Question 2

Name given to a drug by the pharmaceutical company that developed it, also called a TRADE name or PROPRIETARY name

Answer 2

BRAND NAME

Question 3

Name that reflects the CHEMICAL structure of a drug.

Answer 3

CHEMICAL NAME

Question 4

Chemicals that are introduced into the body to bring about change.

Answer 4

DRUGS

Question 5

FDA

Answer 5

FOOD and DRUG ADMINISTRATION

Question 6

Federal agency responsible for the REGULATION and ENFORCEMENT of drug evaluation and distribution policies in the U.S

Answer 6

FDA

Question 7

Drugs sold by their GENERIC name; NOT Brand or Trade name product.

Answer 7

GENERIC DRUGS

Question 8

The original designation that a drug is given when the drug company that developed it applies for the approval process.

Answer 8

GENERIC NAME

Question 9

Process of altering DNA, usually of bacteria, to produce a chemical to be used as a drug

Answer 9

GENERIC ENGINEERING

Question 10

the study of the biological effects of
chemicals

Answer 10

Pharmacology

Question 11

chemicals that are introduced into the body to cause some sort of change.

Answer 11

DRUGS

Question 12

Synthetic version of the active chemical found in a
plant
▪ Main component of the growing alternative
therapy movement

Answer 12

NATURAL RESOURCES ( PLANTS )

Question 13

Used to replace human chemicals that are not
produced because of disease or genetic problems
▪ Genetic engineering
▪ Many of these preparations are now created synthetically

Answer 13

Animal products

Question 14

[ Drug evaluation ]

Chemicals tested on laboratory animals

Answer 14

Preclinical Trials

Question 15

Chemicals tested on human volunteers

Answer 15

Phase I studies

Question 16

Drug tried on informed patients with the disease

Answer 16

Phase II studies

Question 17

Drug used in vast clinical market

Answer 17

PHASE III STUDIES

Question 18

Continual evaluation of the drug

Answer 18

PHASE IV STUDIES

Question 19

Drugs that have been discovered, but are not financially viable and therefore have not been “adopted” by any drug company

Answer 19

ORPHAN DRUGS

Question 20

Chemicals that are produced by companies involved
solely in the manufacturing of drugs
❖ Bioavailability of the drug
❖ “Dispensed as written”
o Important in drugs that have narrow safety margins

Answer 20

GENERIC DRUGS

Question 21

Products that are available without prescription for selftreatment of a variety of complaints.
o Some of these agents were approved as prescription
drugs.
o Later were found to be very safe and useful for patients (example: loratidine).
o Many of these drugs were “grandfathered.

Answer 21

OVER THE COUNTER DRUGS

Question 22

clinical pharmacology—the branch
of pharmacology that deals with drugs; chemicals that are used in medicine for the treatment, prevention, and diagnosis of disease in humans

Answer 22

PHARMACOTHERAPEUTICS

Question 23

having adverse effects on the fetus

Answer 23

TERATOGENIC

Question 24

drugs sold by their chemical name; not brand(or trade) name products

Answer 24

Generic drugs

Question 25

the original designation that a drug is given when the drug company that developed it applies for the
approval process

Answer 25

GENERIC NAME

Question 26

drugs that have been discovered but would not be profitable for a drug company to develop; usually drugs that would treat only a small number of people; these orphans can be adopted by drug companies to
develop

Answer 26

Orphan Drugs