Key Features Flashcards
In a patient presenting with abdominal pain, name the 4 diseases you should know how to manage pharmaco and non-pharmaco.
GERD
- P: antacids, H2-r antagonists, PPIs (4-8wks then deprescribe), prokinetics (metoclopramide, domperidone)
- NP: diet (trigger foods), weight loss, elevate head of bed
PUD:
- P: PPIs (2-12wks then deprescribe), antacids, H2-r antagonists
- NP: diet, smoking cessation, stress management
H.poylori
- triple = amox + clarithro + PPI
- quadruple tx = clarithromycine (tetracyclines) + bismuth salicylates + metronidazole + PPI
Ulcerative Colitis:
- P: 5-ASA (mesalamine), corticosteroids (prednisone), immunomodulators, monoclonal biological therapis (adalimumab), JAK inhibitors
- NP: exercise, stress management, regular FUs, diet as tolerated (not recommended to stop smoking)
Crohn’s:
- P: idem + abx (metronidazole, cipro) , ASA less effective vs UC, surgery more common
- NP: idem + smoking cessation
What are 2 life-threatening situations you should always recognize in a patient with abdominal pain?
Explain management
Ruptured abdominal aortic aneurysm or ruptured ectopic pregnancy.
Management:
1) Stabilize with IVF fluid rescusitation, type and screen, crossmatch, consider blood transfusions. ABC GMOVIE/ACLS if unstable.
2) Once stabilized, refer urgently for definitive management (vascular sx, obstetrics).
What should you always consider in a chronic or recurrent abdo pain?
Always consider cancer in a patient at risk:
bleeding, B sx, family hx, dont hesitate to ask for endoscopy.
Name the extra-GI manifestations of IBD.
- Joints: Arthritis, ankylosing spondylitis.
- Eyes: Uveitis, episcleritis.
- Skin: Erythema nodosum, pyoderma gangrenosum.
- Liver: Primary sclerosing cholangitis (PSC).
Which rythm should you promptly defibrillate?
V-Fib and pulseless or symptomatic ventricular tachycardia.
What are the reversible causes of arrhythmias and how do you recognize/manage them?
1) Hyperkalemia:
- peaked T waves, wide QRS
- stabilize ABC GMOVIE/ACLS
- calcium gluconate for myocardium stabilisation
- insuline with dextrose IV
- sodium bicarb
- nebulized salbutamol (IV if fails)
- epinephrine (5-20mcg IV q2-5min) PRN if requires vasopressor (cant get BP up)
- IV fluids (LR, not NS to avoid hyperchloremic acidosis) vs furosemide depending on volemia
2) Cocaine:
- BP +++, HR ++, sweaty
- diazepam for agitation/htn
- phentolamine for htn (avoid BBs)
- sodium bicarb for QRS widening
- look for emergencies (arrhythmias, seizures, dissection, ACS, arterial thromboembolism)
3) Digoxin toxicity:
- can cause many arrhythmias but mostly think SLOW AFIB
- brady + GI sx
- Digibind (atropine if not available)
- activated charcoal if <2hrs
- treat end-organ dysfct, hyperK+
How do you ensure adequate ventilation in ACLS?
Bag valve mask
(Do not confuse with non-rebreather mask. BVM is for PPV whereas NRM is when patient breaths spont. but needs high flow. NRM prevents exhaled air to mix with the oxygen in reservoir. Think for COPD/Asthma exacerbations.)
During rescuscitation which elements to you assess to decided when you should stop and why?
Assess following circumstances indicating you should stop:
- Asystole
- Long code time
- Poor prognosis
- Living wills
To avoid inappropriate resuscitation.
What should you discuss with patients that have serious medical problems or end-stage disease?
- Code status (do you want us to let natural death occur or would you prefer to be resuscitated?)
- End of life decisions (resuscitation, feeding tubes, levels of treatment)
Readdress issues periodically
[would also add antibiotics, ICU, etc.]
What resources can you use in pediatric resuscitation?
Broselow tape and patient’s weight.
In which patients should you inquire about allergy? and what should be your next step?
All patients
Document it
When a patient says he has an, what should you inquire about? What should you avoid misdiagnosing?
Clarify the manifestations of allergic reactions to diagnose true allergy
Avoid misdiagnosing a viral rash (onset of rash in 1-3 after viral syndrome/fever) or medication intolerance (side effects).
Explain allergy teaching.
- Allergy to food/rx/insect stings
- teach patients AND family
- explain sx of anaphylaxis
- explain self-administration of EpiPen
- Advise to return for immediate reassessment and treatment if anaphylaxis sx or EpiPen used
When do you prescribe an EpiPen?
Every patient who has history of or is at risk of anaphylaxis
On top of an epipen, what should patients with any known drug allergy or previous major allergies get?
A MedicAlert bracelet.
When a patient has an anaphylactic :
- how do you recognize
- how do you manage acutely
- how should you monitor post stabilisation
1) Recognize:
- if min to hours post allergen exposure with BP drop, skin-mucosal involvement, resp sx +/- GI sx
- Exam: tachycardia/pnea, wheezing/stridor, angioedma/urticaria
2) Treat immediately and aggressively:[
- ABC GMOVIE (intubation if airway at risk of obstruction, oxygen)
- epinephrine 0.5mg IM q5min x 3 (adults) or 0.01mg/kg IM max 0.3mg (children)
- can also consider BBs, glucagon
- aggressive IVF
- salbutamol
- adjunctive (antihistamine H1 = diphenhydramine, H2=ranitidine)]
3) Monitor for delayed hypersensitivity reaction [biphasic reaction ad 72hrs] with:
- observation [4-6hrs before dc] [serum tryptase can help early recognition]
and treat with steroids
What is your next step with patients with anaphylaxis of unclear etiology?
Refer to allergist for clarification of the cause.
Name two actions you must take in the particular cases of children with anaphylaction reaction to FOOD?
1) Px an EpiPen for the house, car, school, daycare
2) Advise family to educate child, teachers and caretakers about signs/sx anaphylaxis and about when and how to use for EpiPen.
What 2 diagnosis should you think of in patients with unexplained recurrent respiratory symptoms?
Include allergy-related causes in your differential diagnosis:
1) Sick building syndrome
- sx linked to being in certain buildings (poor ventilation, chemical contaminants, or biological like mold)
2) Seasonal allergy
- sx vary per season
- tree pollen in spring, grass pollen in summer, weed pollen in fall.
- tx antihistamines H1 (diphenhynamine/benadryl) , nasal corticosteroids (fluticasone/flonase), decongestants (pseudo ephedrines)
- NP: keep windows closed, air filters, stay indoors.
In patients with anemia, what risks would make you consider prompt transfusion or volume replacement necessary?
In CHF/angina:
- lower threshold to give blood transfusion (HB<80-100, compared Hb<70-80)
- because less ability to compensate with their limited oxygen supply.
Volume status:
- consider volume replacement IVF if hypovolemic/shock (low BP, tachy)
In CHF think of the risk of TACO (transfusion associated circulatory overload):
- manifests as acute resp distress + pulmonary edema on CXR
- prevent with slow transfusion rate + diuretics + HYPERtensive
TRALI (transfusion related acute lung injury):
- immune rx between blood’s Ab and patient’s WBC
- idem as TACO (ARS+PE) but HYPOtensive/fever
- tx = supportive care with O2 and IVF
- prevent with donnor screening (avoid multiparous women)
In anemia what should you always order with your CBC?
1) MCV or smear test to classify micro/normo/macrocytic:
- Micro = TAILS (see picture)
- Normo = hemolysis HEADS (see picture), blood loss, chronic disease (CKD, chronic inflam, neo)
- Macro = B12/B9 deficiency, pregnancy, ETOH use disorder/liver disease, hypoT4, myelodysplasic
**Smear in IDA: microcytosis, hypochromia, anisocytosis, thrombocytosis, poikilocytosis (oval/pencil shaped)
2) In ALL patients, order iron profile:
- ferritin (low in IDA)
- serum iron level (low in IDA)
- total iron binding capacity (high in IDA)
- transferrin saturation (low in IDA)
When should you consider and look for anemia?
1) Wether sympatomatic or not:
- at risk of blood loss (anticoagulation, elederly taking NSAIDs)
- pts with hemolysis (mechanical valves!!)
2) New/worsening symptoms in :
- CHF
- angina
What should you consider first in macrocytic anemia? And what symptoms should you look to make a particular diagnosis?
1) Consider the possibility of vitamine B12 deficiency
2) Look for neurological symptoms (see picture) of B12 deficiency to diagnose pernicious anemia.
- pernicious anemia is more likely to manifest with neurologic symptoms than other causes of B12 deficiency
When should you consider looking for anemia during well-baby care assessment?
1) High risk populations (living in poverty)
2) High-risk patients:
- pale
- low iron diet
- poor weight gain