Key Chemistry Word Associations Flashcards
Process in which there is a loss of hydrogen electrons
Oxidation
Process in which there is a gain of hydrogen electrons
Reduction
Replacement of hydrogen by a carboxyl group (-COOH)
Carboxylation
Substance which speeds up the rate of a chemical reaction
Enzyme
Inactive precursor protein with an additional peptide attached
Pro-enzyme
Enzyme that catalyzes the addition of a carboxyl group
Carboxylase
Removal of the carboxyl group (-COOH)
Decarboxylation
An enzyme that catalyzes the release of CO2 from compounds
Decarboxylase
Reaction that combines H2O with a salt to produce acid and base
Hydrolysis
Enzyme that causes hydrolysis
Hydrolase
Movement of a phosphate (PO4) form one molecule to another
Phosphorylation
Enzyme which adds a phosphate to an organic compound
Phosphorylase
Enzyme that removes a phosphate form an organic compound
Phosphatase
Enzyme that adds a high-energy phosphate to an organic compound
Kinase
Enzyme that catalyzes the transfer of one group to another
Transferase
Enzyme that makes an isomer (same chemical composition)
Isomerase
Molecule with the same composition but different chemical structure
Isomer
Isomerase enzyme which changes the configuration of a molecule
Mutase
Number of factors that affect enzyme activity
3
Temperature, pH and concentration of the substrate
Affects enzyme activity
Maximum velocity of a reaction
Vmax
Michaelis-Martern constant
Kmax
The amount of substrate required to reach 1/2 of the Vmax
Kmax
A substance which slows down the rate of an enzyme reaction
Inhibitor
Competition and allosterism
Enzymatic regulation
Actively competes with substrate for the active site
Competition
Change in activity by acting on a site other than the active site
Allosterism
Chemical bond between two amino acids
Peptide bond
Chemical bond between the base bases found in DNA
Hydrogen bond
Chemical bond between glycerol and fatty acids
Ester bond
Chemical bond between two sugars
Glycosidic bind
Chemical bond between nucleotides
Phosphodiester
Site of all pathways except the Krebs cycle and 1st half of the urea cycle
Cytosol
Site of the Krebs cycle and 1st half of the urea cycle
Mitochondria
Constituents of starch
Amylose and Amylopectin
Long, unbranched chains of glucose linked at C1 and C4 (a1,4 link)
Amylose
Fewer branches of glucose with a1,4 and 1,6 linked branches
Amylopectin
Comprised of glucose and fructose; found in table sugar and fruit
Sucrose
Contains galactose linked glucose; found in milk; B1,4 link
Lactose
Form in which glucose is stored in skeletal muscle and liver
Glycogen
Aldopentose (5 Carbon) sugar
Ribose
Ketohexose (6 Carbon) sugar
Fructose
Crucial step that controls how fast or slow the pathway goes
Rate limiting step
The most important rate limiting step in glycolysis
Phosphofructokinase
Steps in glycolysis at which ATP is used
Steps 1 and 3
Steps in ATP in which ATP is produced
Steps 7 and 10
Step in glycolysis at which NADH is produced
Step 6
Number of pyruvate molecules produced from one glucose in glycolysis
2
Main fate of pyruvate
Converted to Acetyl CoA
Alternate fates of pyruvate
Lactate and Alanine
Number of carbon molecules in pyruvate
3
Number of carbon molecules in acetoacetate
2
Making glucose from pyruvate, lactate, glycerol, fatty and amino acids
Gluconeogenesis
Irreversible steps in glycolysis that are replaced in gluconeogenesis
Steps 1, 3 and 10
Location of gluconeogenesis
Mitochondria and cytoplasm
Lactate is converted to pyruvate which is covered to glucose
Sequence of events
Vitamin deficiency which results in excess lactic acid production
Biotin deficiency
Rate limiting step in gluconeogenesis
F1,6 Bisphosphatase
Hormone which inhibits gluconeogenesis
Insulin
Location of Krebs cycle
Mitochondrial Matrix
Steps in the Krebs cycle at which NADH is produced
Steps 3 + 4 = 7
Type of enzyme which facilitates the production of NADH
Dehydrogenase
Destination of the energy harvested from the Krebs cycle
Electron Transport Chain
Number of ATPs generated from 1 NADH
3 ATP
Number of ATPs generated from 1 FADH2
2 ATP
Number of NADH, FADH2 and GTP generated by one Krebs cycle
3 NADH, 1 FADH2 and 1 GTP
Number of Krebs cycles to completely break down 1 glucose
2
Number of ATP produced from breakdown of one glucose in glycolysis
4 ATP