Key assets in MM Flashcards
Abecma: INN, company, MoA and Target
ide-cel, BMS, CAR-T, BCMA
Abecma: what is it approved in?
5L+ RRMM
Abecma: what trial gained its approval and when?
Phase 2 KarMMa trial, 2021
Mezigdomide: company, MoA
BMS, CELMOD
What drugs are approved in 5L+ RRMM (Drug names + INNs)
Blenrep (belantamab mafadorin), Abecma (ide-cel), Carvykti (cilta-cel)
What drugs are approved in NDMM (TI)(Drug name + INN)
Darzalex, daratumumab
What combinations are approved in 2L+ RRMM
XVd, Dara+Pd, Dara +Kd, IsaKd
What combination is approved in 3L+ RRMM
Isa + Pd
What combinations are approved in 2L+ including Amgen’s Kyprolis?
DKd, IsaKd
Empliciti: INN, company, MoA and target
elotuzumab, BMS, CS1 mAb
Iberdomide: company, MoA
BMS, CELMOD
Pomalyst: INN, company, MoA
pomalidomide, BMS, IMiD
Revlimid: INN, company, MoA
lenalidomide, BMS, IMiD
zevor-cel: company, MoA and target
Cargsen, BCMA, CAR-T
Pepaxti: INN, company, MoA
melflufen, oncopeptides, alkyliting agent
Elranatamab: company, MoA and target
Pfizer, BCMA TCE
Venclexta/Venclyxto: INN, company, MoA and target
venetoclax, Abecma, BCL2i (small molecule)
Sarclisa: INN, company, MoA and target
isatuximab, Sanofi, CD38 mAb
Darzalex: INN, company, MoA and target
daratumumab, JNJ, CD38 mAb
Velcade: INN, company, MoA and target
bortezomib, Takeda, PI
Ninlaro: INN, company, MoA and target
ixazomib, Takeda, PI
Modakafusp alpha: company + target
Takeda + CD38
Tecvayli: INN, company, MoA + Target
teclistamab, JNJ, BCMA TCE