Key Area 1 Flashcards

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1
Q

What is a metabolic pathway

A

Integrated and controlled pathways of enzyme catalysed reactions within a cell

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2
Q

What steps can metabolic pathways have

A

Reversible, irreversible and alternative routes

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3
Q

Reactions with in metabolic pathways can be…

A

Anabolic or catabolic

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4
Q

What’s an anabolic reaction

A

Builds large molecules from small building blocks - requires energy

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5
Q

What’s a catabolic reaction

A

Breaks down complex molecules - releases energy

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6
Q

3 things embedded with in membrane

A

Protein pumps
Protein pores
Enzymes

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7
Q

What does a protein pump do

A

Transfer specific ions across membrane

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8
Q

What do protein pores do

A

Allow larger molecules to move across membrane

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9
Q

What are metabolic pathways controlled by

A

Presence or absence of particular enzymes and the regulation of the rate of reaction of key enzymes

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10
Q

What is induced fit

A

When active site slightly changes to better fit substrate

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11
Q

Affinity of substrates

A

High

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12
Q

Affinity of product

A

Low

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13
Q

What is a inhibitor

A

A substance which decreases the rate of an enzyme controlled reaction

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14
Q

What is an inhibitor

A

A substance which decreased the rate of an enzyme controlled reaction

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15
Q

3 types of inhibitors

A

Competitive
Non competitive
Feedback

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16
Q

What does a competitive inhibitor do

A

Compete for available active site - active site gets blocked so substrate is unable to bind - reaction rate is reduced

17
Q

What is competitive inhibition

A

Compete for active site - active site is now blocked so substrate unable to bind - reaction rate reduced
Increasing substrate concentration will reverse effect

18
Q

What is non competitive inhibitions

A

Does not compete - bind to allosteric site - changes shape of enzyme - active site shape permanently changed - substrate unable to bind - enzyme substrate complex not made

19
Q

What is feedback Inhibition

A

As concentration of end product builds up some of it binds to enzyme
Slowing down reaction rate in pathway