Kety Flashcards

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1
Q

Aim

A

to see if there’s a genetic basis of schizophrenia

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2
Q

sample

A

34 patients from Denmark and 33 matched pairs controls (age, gender, age of adoption, social class)

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3
Q

IV n DV

A

IV = SZ sufferers and control group with no history of MI
DV = prevalence of SZ - related MI from family members

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4
Q

Method

A

• 463 adopted and bio families
• Danish family records used to locate both relatives
• 4 psychiatrists did blind test on each case to diagnose family members with SZ or not (removed 4 as couldn’t agree) - didn’t know if bio or adopted families
• identities revealed and assigned to adoptive family groups (IA or CA) and biological family groups (IB or CB)

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5
Q

Results

A

Of 150 biological relatives in index cases 13 (8.7%) had diagnosis of SZ
Of 156 biological relatives in control cases 3 (1.9%) had diagnosis of SZ

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6
Q

Weakness ETHNO

A

ethnocentric as all of SZ adoptees and families from one location and culture (Denmark) - results about genetics influences SZ might not apply to wider population

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