Ketamine

Question 1

Name a dissociative anesthetic drug?

Answer 1

Ketamine

Question 2

What drug concoction do we use ketamine in?

Answer 2

• Kitty magic (ketamine, dexmedetomidine, buprenorphine)

- Triple dip (large animal) guaifenesin, xylazine, ketamine

Question 3

Name the receptor for ketamine?

Answer 3

Non-competitive antagonist (at the glutamate receptor)

Question 4

NMDA is involved with ________ and ______

Answer 4

CNS hyper sensitization and neuropathic pain

Question 5

Anesthetic doses of ketamine cause?

Answer 5

excitatory effects

Question 6

Decreased doses of ketamine don’t act on and causes ____ in people?

Answer 6

primary pain and causes hallucinations

Question 7

Does it cross the BBB?

Answer 7

wide distribution crosses the BBB

Question 8

Route of Administration?

Answer 8

IV mainly

IM adm. causes pain

Question 9

Can it be used as a sole analgesic?

Answer 9

No not recommended (not used alone as a chemical restraint?

Question 10

_____ + _____ to treat acute pain

Answer 10

ketamine + opioid = acute pain treatment

Question 11

Reversible or irreversible

Answer 11

irreversible (non competitive)

Question 12

Describe to me about ketamine and who it is of good use for?

Answer 12

Good for asthmatics because of bronchodilation

Question 13

What do they mean my ketamine being a somatic analgesic?

Answer 13

Increase pain relief of the muscle and skin more than visceral (short duration)

Question 14

What effects on GI?

Answer 14

increased salivation

Question 15

How is this drug post surgery?

Answer 15

Good because it increases feeding behavior after surgery

Question 16

What main effects on the CNS does it have?

Answer 16

Decreased thalamocortical system and increases limbic system dissociation

Question 17

Why can’t we use this with brain trauma patients?

Answer 17

Increased ICP and IOP (can cause corneal ulcerations) don’t use if history of seizures

Question 18

Contraindicated with ___ Ds. in cats

Answer 18

renal

Question 19

Muscle relaxation?

Answer 19

no muscle relaxation by itself

Question 20

MLK

Answer 20

Morphine
Lidocaine
Ketamine

Question 21

FLK (Analgesic CRI best)

Answer 21

Fentanyl
Lidocaine
Ketomine

Question 22

CV effects?

Answer 22

Increased CO CVP HR and CBF

Question 23

Anesthesia effects?

Answer 23

takes 3-5 minutes to start working

lasts 20-45 minutes

recovery 2-10 hours

consciousness not completely loss so don’t disturb