Ketamine Flashcards
Name a dissociative anesthetic drug?
Ketamine
What drug concoction do we use ketamine in?
- Kitty magic (ketamine, dexmedetomidine, buprenorphine)
- Triple dip (large animal) guaifenesin, xylazine, ketamine
Name the receptor for ketamine?
Non-competitive antagonist (at the glutamate receptor)
NMDA is involved with ________ and ______
CNS hyper sensitization and neuropathic pain
Anesthetic doses of ketamine cause?
excitatory effects
Decreased doses of ketamine don’t act on and causes ____ in people?
primary pain and causes hallucinations
Does it cross the BBB?
wide distribution crosses the BBB
Route of Administration?
IV mainly
IM adm. causes pain
Can it be used as a sole analgesic?
No not recommended (not used alone as a chemical restraint?
_____ + _____ to treat acute pain
ketamine + opioid = acute pain treatment
Reversible or irreversible
irreversible (non competitive)
Describe to me about ketamine and who it is of good use for?
Good for asthmatics because of bronchodilation
What do they mean my ketamine being a somatic analgesic?
Increase pain relief of the muscle and skin more than visceral (short duration)
What effects on GI?
increased salivation
How is this drug post surgery?
Good because it increases feeding behavior after surgery
What main effects on the CNS does it have?
Decreased thalamocortical system and increases limbic system dissociation
Why can’t we use this with brain trauma patients?
Increased ICP and IOP (can cause corneal ulcerations) don’t use if history of seizures
Contraindicated with ___ Ds. in cats
renal
Muscle relaxation?
no muscle relaxation by itself
MLK
Morphine
Lidocaine
Ketamine
FLK (Analgesic CRI best)
Fentanyl
Lidocaine
Ketomine
CV effects?
Increased CO CVP HR and CBF
Anesthesia effects?
takes 3-5 minutes to start working
lasts 20-45 minutes
recovery 2-10 hours
consciousness not completely loss so don’t disturb
