Keratosis Lichenoides chronica

Question 1

Presentation of keratosis lichenoides chronica:

Answer 1

• symmetric eruption on extremities and trunk comprised of violaceous keratotic papules coalescing into plaques, arranged in a linear or reticulate pattern, in association with a seb derm-like eruption of face

Question 2

Classic clue for Dx of Keratosis lichenoides chronica?

Answer 2

• greasy, sebopsoriasis- like centrofacial plaques in addition to linear or reticulate violaceous papules/plaques

Question 3

Histology of Keratosis Lichenoides chronica?

Answer 3

• exactly the same as lichen planus:
• orthohyperkeratosis
• wedge-shaped hypergranulosis
• irregular acanthosis w/ saw-toothed rete ridges
• civatte bodies (apoptotic keratinocytes in the basal layer
• lichenoid lymphocytic infiltrate