Kawasiki disease

Question 1

Kawasaki criteria

Answer 1

1. Fever for > 5 days, and
2. Four of the following symptoms:
   • Bulbar conjunctival injection
   • Desquamation of the finger and toe tips, indurative edema
   • Erythema, fissuring, and crusting of the lips, strawberry tongue, and diffuse mucosal injection of the oropharynx
   • Morbilliform truncal exanthem
   • Cervical lymphadenopathy

Question 2

Kawasaki disease or mucocutaneous lymph node sd def

Answer 2

most common causes of generalized vasculitis in children

Question 3

Kawasaki can be fatal bcoz of

Answer 3

1. giant aneurysm formation

2. thrombosis or rupture of the coronary arteries leading to myocardial infarction

Question 4

Kawasaki and scarlet fever

Answer 4

• Scarlet fever have positive strep throat test and normal-appearing lips
• Kawasaki disease : negative strep throat test and inflamed lips

Question 5

Latex agglutination test

Answer 5

more rapid but less accurate in Diagnosis of scarlet fever

Question 6

Scarlet fever tt

Answer 6

ten-day Penicillin V

if allergic, can use erythromycin or clindamycin

Question 7

tt of scarlet fever w penicillin does not prevent

Answer 7

post-streptococcal glomerulonephritis

Question 8

Kawasaki lab

Answer 8

increased acute phase reactants : erythrocyte sedimentation rate (ESR) and C-reactive protein, leukocytosis, normochromic-normocytic anemia and thrombocytopenia

Question 9

Kawasaki disease mgmt

Answer 9

hospitalized and treated w IV immune globulin IVIG and high-dose aspirin

Question 10

Aspirin in Kawasaki disease

Answer 10

fever and arthritis

Question 11

IVIG intravenous immune globulin in Kawasaki

Answer 11

reduce the incidence of coronary artery aneurysms

Question 12

untt Kawasaki

Answer 12

up to 25%, develop coronary artery aneurysms