Kaplan Review Flashcards
Incidence of chromosomal abnormalities 25 and 35
25 - 1/250
35 - 1/365
CVS - risk of pregnancy loss, age optimal, what you find
0.7% risk of pregnancy loss
done at 12-18 weeks
fetal karyotyping
amniocentesis - risk of pregnancy loss, age, what you find
0.5% risk of pregnancy loss
done at 15-20 weeks
genetic purposes or Rh isoimmunization
risk of NTD
1-2/1000
major teratogenic risk week
postconception weeks 4-8
hcg is produced by and peaks at
placental syncytiotrophoblast, starts at 10 days peaks at 9-10 weeks
- maintain corpus luteum production of progesterone
- high levels are twin, moles, choriocarcinoma, embryonal carcinoma
hpl
similar to growth hormone and prolactin
- contributes to predisposition of pregnancy to glucose tolerance and diabetes
progesterone
produced by corpus luteum 6-7, then corpus luteum and placenta 7-9, then placenta 9 weeks
estradiol
estrogen during nonpregnant reproductive years
estriol
estrogen during pregnancy
estrone
estrogen during menopause
change in blood pressure
systolic and diastolic decrease, nadir by 24-28 weeks
plasma volume is… up, down, same
increased by 50%
PVR… up, down, same
decreases by 30%
cardiac output… up, down, same
increases by 50%
WBC…up, down, same
increases during pregnancy
coag factors…up, down, same and which ones
increases, 7, 8, 9, C
gastric motility…up, down, same
decreases, emptying time increases