Kaplan High Yield Ob Flashcards
pre-viable vs preterm vs term fetus
<24 weeks vs 25-37 weeks vs 38-42 weeks
Goodell sign
Ladin sign
Chadwick sign
- softening of cervix; 4 weeks
- softening of midline of uterus; 6 weeks
- blue discoloration of cervix/ vagina; 6-8 weeks
what is the cause of morning sickness?
inc progesterone, estrogen, beta-HCG
physiologic changes during pregnancy
- cardiac
- GI
- renal
- hematology
- cardiac: inc CO, dec BP (progesterone-mediated vasodilation)
- GI: morning sickness, GERD, constipation
- renal: inc GFR (from inc plasma volume); inc size of kidney/ ureter (= physiologic hydronephrosis from compression of ureters)
- heme: anemia (from inc plasma volume); hyper-coagulable state
triple vs quad screen? when are they done? what is it used for?
- MSAFP + beta-HCG + estriol
- MSAFP + beta-HCG + estriol + inhibin A
- performed during 2nd tri
- used to screen for chromosomal abnormalities
Braxton-Hicks contractions vs preterm labor
- B-H = sporadic contractions withOUT cervical changes
- preterm labor = regular contractions with cervical changes before 37 weeks
3rd tri tests?
- CBC –> for anemia
- glucose load test
- cervical and rectovaginal cultures –> for chlamydia/ gonorrhea and GBS
chorionic villus sampling: when? what does it dx? how?
- when: 10-13 weeks
- dx: obtains fetal karyotype
- how: aspirate chorionic villi from placenta via inserting a catheter to the intrauterine cavity (trans-abdominally vs -vaginally)
amniocentesis: when? what does it dx? how?
- when: after 14 weeks
- dx: obtains fetal karyotype
- how: withdraws amniotic fluid via inserting a needle trans-abdominally
fetal blood sampling: when? what does it dx? how?
- when: in mom’s with Rh isoimmunization or when fetal CBC is needed
- dx: anemia of the fetus
- how: withdraw blood from the umbilical cord via a needle trans-abdominally
risk factors for ectopic pregnancy?
- PID
- IUD
- previous ectopic
ectopic pregnancy px
-px: unilateral lower abdominal or pelvic pain + vaginal bleeding + hypotensive (if ruptured)
ectopic pregnancy tx
- medical: get CBC + type/screen + transaminases + beta-HCG –> administer methotrexate (heptotoxic) –> watch for changes in beta-HCG
- proceed to surgery if ruptured* OR if no changes in beta-HCG
- surgery: give fluids + blood products + pressers if unstable
- salpingostomy or salpingectomy
contraindications to methotrexate?
- immunodeficiency –> methotrexate = immunosuppresive
- liver disease
- noncompliant –> may need f/u for 2nd dose
- ectopic > 3.5cm
- fetal heart beat heard
abortion =
a pregnancy that ends before 20 weeks or a fetus <500g
types of abortion
- complete
- incomplete
- inevitable
- threatened
- missed
- septic
- no products of conception left in uterus
- some products of conception left in uterus
- intact products of conception + intrauterine bleeding + cervical dilation
- intact products of conception + intrauterine bleeding
- death of fetus; no bleeding or cervical changes
- infection of uterus
multiple gestation px
- exponential growth of uterus
- rapid weight gain by mother
- elevated beta-HCG & MSAFP more than expected for GA
twin transfusion syndrome
anastomosis of vessels causing 1 twin to receive most of the supply –>
- 1 twin becomes anemic –> hydrops fettles
- 1 twin becomes fluid overloaded
preterm labor definition, risk factors
= contractions + cervical dilation before 37 weeks
-risk factors: PROM, multiple gestation, placental abruption, previous hx of preterm labor, chorioamnionitis, preeclampsia
preterm labor tx
- stop delivery if:
- deliver if:
- stop if 24-33 GA or 600-2500g
- given betamethasone + tocolytics so that lungs can mature
-deliver if 34-37 GA (lungs already matured)
tocolytics definition, list
-slow progression of cervical dilation by decreasing uterine contractions
- magnesium sulfate
- CCBs (nifedipine)
- beta agonists (terbutaline)
premature rupture of membranes (PROM) definition, dx
=rupture of chorioamniotic membrane –> “gush of fluids” from vagina
-dx: sterile* speculum exam + fluid in posterior turns nitrazine paper blue + ferning on microscopy
PROM tx
- chorioamnionitis
- term infant, no infection
- preterm infant
- deliver now
- wait for spontaneous delivery (induce after 12 hours of waiting)
- betamethasone + tocolytic + ampicillin + azithromycin