K+ Flashcards
major mechanism of transport in the proximal tubule
Na-K-ATPase pump in the basolateral membrane
a-catecholamines
- effect on K+
decrease cell uptake (hyperkalemia)
how does aldosterone enhance acid secretion of K+
production of systemic alkalosis
principal cells
- reabsorb
- secrete
- Na+, H2O
- K+
during volume expansion,
what increases distal K+ secretion and what decreases it
3 most important factors that stimulate potassium secretion
- increased ECF K+
- aldosterone
- increased tubular flow rate
alkalosis
- effect on K+
increase cell uptake (hypokalemia)
effect on anion delivery on K+
increases K+ secretion
- acts as osmotic diuretic and increases fluid flow rate
cell damage
- effect on K+
- mechanism
decrease cell uptake (hyperkalemia)
release of intracellular contents
strenuous exercise
- effect on K+
- mechanism
increase cell efflux of K+ via alpha catecholamines
during volume contraction,
what increases distal K+ secretion and what decreases it
effect of glucocorticoids on K+
increases K+ secretion via binding of mineralcorticoid receptor, increasing GFR, and increasing fluid flow rate
role of epinephrine on K+
- decreases uptake into cells extrarenally
- increases K+ secretion
beta-intercalated cells
- reabsorb
- secrete
- H+, Cl-
- K+, HCO3-
after K+ is secreted into cortical collecting duct, what part of the duct is it reabsorbed at
outer medullary and inner medullary
during high water intake,
what increases distal K+ secretion and what decreases it
ADH does both
in acidosis,
what increases distal K+ secretion and what decreases it
