Juvenile Idiopathic Arthritis

Question 1

Define Juvenile Idiopathic Arthritis

Answer 1

All forms of arthritis that develop before 16 years of age and that persist for a minimum of 6 weeks

Question 2

What are the clinical subsets of JIA?

Answer 2

1. Systemic Arthritis
2. Oligoarthritis
3. Rheumatoid factor- positive polyarthritis
4. Rheumatoid factor- negative polyarthritis
5. Enthesitis-Associated Arthritis
6. Psoriatic Arthritis
7. Undifferentiated Arthritis

Question 3

How does JIA differ from RA?

Answer 3

1. Oligoarthritis - more common
2. Systemic Disease - more common
3. Large Joints - more common
4. No Rheumatoid Noules/Factor
5. ANA Serpositivity - common

Question 4

How is JIA similar to RA?

Answer 4

MULTIFACTORIAL (Genetic and Environemnt)

Inflammatory Synovitis and Morphologic Changes are similar

Question 5

JIA - Systemic Arthritis

Answer 5

Rapid Onset
High Fever
Skin Rash
Hepatosplenomegaly

Question 6

JIA - Oligoarthritis

Answer 6

Four or FEWER Joints affected 
No psoriasis
HLA-B27
Asymetric
YOUNG (<6yo)
Iridocylitis
(+) ANA

Question 7

JIA - Rheumatoid Factor Positive Polyarthritis

Answer 7

Similar to Adult Form

Teenage Girls

Question 8

JIA - Enthesitis-related arthritis

Answer 8

Male (<6yo)
HLA-B27 (like Oligoarthritis)
Tendon and Ligament Insertions in LE