Just notes. Struggle bus notes. Flashcards

1
Q

Clinical Presentation Acute hemolysis

A

Fever, pain, Hypotension, rapid onset

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2
Q

Major Complications Acute hemolysis

A

DIC, Renal failure, Shock

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3
Q

Causes acute reaction hemolysis

A

Complement activation

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4
Q

Essential lab tests Acute hemolysis

A

Clerical/visual checks, ABO re type, Test for hemolysis

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5
Q

Management for acute hemolysis

A

Treat DIC and shock, support renal functionP

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6
Q

Prevention Acute hemolytic

A

System designs to avoid clerical errors

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7
Q

Clinical presentation Delayed hemolysis

A

Mild jaundice, unexplained H/H dropMajor

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8
Q

Major complications Delayed hemolysis

A

none

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9
Q

Causes delayed hemolysis

A

anamnestic

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10
Q

essential lab tests delayed hemolysis

A

DAT, H/H, bili, haptoglobin

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11
Q

Management delayed hemolysis

A

provide antigen negative units

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12
Q

Prevention delayed hemolysis

A

system designed to prevent clerical and technical errors

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13
Q

Delayed antibodies

A

Kidd, Duffy, Kell, MNS

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14
Q

Acute antibodies

A

ABO, Rh, Kell

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15
Q

FNHTR

A

Most often called
Caused by HLA reactions on WBC

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16
Q

Prevent FNHTR

A

Tylenol
LRBC

17
Q

Allergic reaction TFRXN

A

IgA allergy in plasma
Rash, itching, trouble pbreathing
Maculopapular rash = real bad

18
Q

Prevention allergice TFRXN

A

Different dono blood product

19
Q

GVHD

A

TFS’d product has Lymphs that attack the recipient
Macopapulat rash, 90% mortality rate
pancytopenia lab finding

20
Q

GVHD prevention

A

irradiated products
Stem cell transplant, immunosuppresent

21
Q

TRALI

A

Antibodies in donor are reactive to recipients WBCs
Severe respiratory distress
Severe hypoxia

22
Q

TRALI prevention

A

Increasing donor deferal to females that have been pregnant and males that have recieved transfusionsT

23
Q

TACO

A

Too much fluid. Heart can’t pump out
Dyspnea, coughing, hypertension, tachychardia

24
Q

TACO treatment

A

stop transfusion
supportive therapy
O2 supplement

25
Q

TACO prevention

A

check lab values before transfusion

26
Q

Sepsis

A

Plt issue
Increase temp really high really fast

27
Q

Sepsis prevention

A

plt expiration dates
proper storrage

28
Q

sepsis findings

A

blood culture matches the culture on product

29
Q

Iron Overload

A

Yellow tinge skin
Multi organ failure
accumulation of iron in tissues

30
Q

Iron overload prevention

A

tfsn of < 20 red cells per year or washed cells

31
Q

Citrate toxicity

A

ingestion of citrate - stops Ca
Hypocalcemia

32
Q

Citrate toxicity treatment

A

Give Ca

33
Q

post transfussion purpura

A

Anti plt antibody
Anti-HPA-1
Thrombocytopenia, bleeding, peticheia

34
Q

anti plt antibody treatment

A

pool plt

35
Q
A