Just notes. Struggle bus notes.

Question 1

Clinical Presentation Acute hemolysis

Answer 1

Fever, pain, Hypotension, rapid onset

Question 2

Major Complications Acute hemolysis

Answer 2

DIC, Renal failure, Shock

Question 3

Causes acute reaction hemolysis

Answer 3

Complement activation

Question 4

Essential lab tests Acute hemolysis

Answer 4

Clerical/visual checks, ABO re type, Test for hemolysis

Question 5

Management for acute hemolysis

Answer 5

Treat DIC and shock, support renal functionP

Question 6

Prevention Acute hemolytic

Answer 6

System designs to avoid clerical errors

Question 7

Clinical presentation Delayed hemolysis

Answer 7

Mild jaundice, unexplained H/H dropMajor

Question 8

Major complications Delayed hemolysis

Answer 8

none

Question 9

Causes delayed hemolysis

Answer 9

anamnestic

Question 10

essential lab tests delayed hemolysis

Answer 10

DAT, H/H, bili, haptoglobin

Question 11

Management delayed hemolysis

Answer 11

provide antigen negative units

Question 12

Prevention delayed hemolysis

Answer 12

system designed to prevent clerical and technical errors

Question 13

Delayed antibodies

Answer 13

Kidd, Duffy, Kell, MNS

Question 14

Acute antibodies

Answer 14

ABO, Rh, Kell

Question 15

FNHTR

Answer 15

Most often called
Caused by HLA reactions on WBC

Question 16

Prevent FNHTR

Answer 16

Tylenol
LRBC

Question 17

Allergic reaction TFRXN

Answer 17

IgA allergy in plasma
Rash, itching, trouble pbreathing
Maculopapular rash = real bad

Question 18

Prevention allergice TFRXN

Answer 18

Different dono blood product

Question 19

GVHD

Answer 19

TFS’d product has Lymphs that attack the recipient
Macopapulat rash, 90% mortality rate
pancytopenia lab finding

Question 20

GVHD prevention

Answer 20

irradiated products
Stem cell transplant, immunosuppresent

Question 21

TRALI

Answer 21

Antibodies in donor are reactive to recipients WBCs
Severe respiratory distress
Severe hypoxia

Question 22

TRALI prevention

Answer 22

Increasing donor deferal to females that have been pregnant and males that have recieved transfusionsT

Question 23

TACO

Answer 23

Too much fluid. Heart can’t pump out
Dyspnea, coughing, hypertension, tachychardia

Question 24

TACO treatment

Answer 24

stop transfusion
supportive therapy
O2 supplement

Question 25

TACO prevention

Answer 25

check lab values before transfusion

Question 26

Sepsis

Answer 26

Plt issue
Increase temp really high really fast

Question 27

Sepsis prevention

Answer 27

plt expiration dates
proper storrage

Question 28

sepsis findings

Answer 28

blood culture matches the culture on product

Question 29

Iron Overload

Answer 29

Yellow tinge skin
Multi organ failure
accumulation of iron in tissues

Question 30

Iron overload prevention

Answer 30

tfsn of < 20 red cells per year or washed cells

Question 31

Citrate toxicity

Answer 31

ingestion of citrate - stops Ca
Hypocalcemia

Question 32

Citrate toxicity treatment

Answer 32

Give Ca

Question 33

post transfussion purpura

Answer 33

Anti plt antibody
Anti-HPA-1
Thrombocytopenia, bleeding, peticheia

Question 34

anti plt antibody treatment

Answer 34

pool plt