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Haem Molecules And Antibodies and Toxcitiy Of Chemo > Just Learn These! > Flashcards

Just Learn These! Flashcards

1
Q

What is treatment for low grade indolent NHL? - non Hodgkin lymphoma? If asymptomatic

A

Watch and wait

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2
Q

I’m stage 1 non Hodgkin lymphoma what is treatment?

A

Local radiotherapy to nodal sites

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3
Q

What is gold standard treatment for non Hodgkin lymphoma ?

A

R- Chop
Cyclophosphamide
Doxorubicin
Vinicristine
Prednisolone

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4
Q

What cells are present in Hodgkin lymphoma?

A

Reed sternberg cells

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5
Q

Which lymphoma has alcohol induced painful lymphadenopathy ?

A

Hodgkin

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6
Q

What organs can be expanded in Hodgkin lymphoma?

A

Hepatomegaly and splenomegaly

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7
Q

What is treatment for Hodgkin lymphoma?

A

ABVD : adriamycin (doxorubicin) , bleomycin, vinblastine, dacarbazine

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8
Q

If Hodgkin lymphoma relapses occurs within more than 1 year after completion what is treatment ?

A

ESHAP - etoposide, cytosine, arabinoside, methylpred

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9
Q

Which condition are smudge cells seen in?

A

CLL

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10
Q

Which cells are tear drop poikocytes seen in?

A

Primary myelofibrosis

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11
Q

What cells can micocytic anaemia cause?

A

Hypersegments polymorphs/ neutrophils

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12
Q

What is seen in splenectomy and sickle cell

A

Howell jolly bodies

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13
Q

What cells are seen in G6PD

A

Heinz

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14
Q

Which chemo agent causes neurotoxicity

A

Asparagine

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15
Q

What chemo agent causes ototoxic and nephrotoxic

A

Cisplatin

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16
Q

Which chemo agents cause peripheral neuropathy?

A

Vincristine and vinblastine

17
Q

Which Chen agent causes pulmonary fibrosis

18
Q

Which chemo agent causes cardiotoxicity

A

Doxorubicin

19
Q

Which chemo agent causes nephro/ bladder toxicity plus SIADH?

A

Cyclophosphamide

20
Q

ANA

A

SLE - sensitive but not specific

21
Q

Anti DSDNA

A

SLE - specific

22
Q

Anti ro and anti La

23
Q

Anti centromere

A

Limited cutaneous systemic sclerosis

24
Q

Anti scl

A

Diffuse systemic sclerosis

25
Q

Anti Jo

A

Polymyositis and dermatomyositis

26
Q

Anti Mi2

A

Dermatomyositis - suggest good prognosis

27
Q

C anca

A

Wegner - granulomatous with polangitis

28
Q

P anca

A

UC
Chugg struss - eosinophilic
Microscopic polyangitis

29
Q

Anti wndomysial antibodies

30
Q

Anti smooth muscle (ASMA) muscle

A

Autoimmune hepatitis - type 1

31
Q

Anti LKM liver kidney microtonal

A

Autoimmune hep type 2

32
Q

Anti mitochondrial (AMA)

33
Q

Anti Acetylcholine

34
Q

Anti MUSK - muscle specific kinase

A

MG - seronegative subtype

35
Q

Anti voltage gated potassium channel

A

Limbic encephalitis, neuromyotonia

36
Q

Antiphospholipid syndrome?

A

Lupus anticoag

Anti cardio lipin
Anti b2glycoprotein

37
Q

Cold agglutin antibodies (igm)

A

Cold agglutin disease secondary to infections like mycoplasma pneumonia

Haem Molecules And Antibodies and Toxcitiy Of Chemo (1 decks)

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