julia specific notes for midtermn Flashcards

1
Q

MCC of

Epiglottitis

laryngomalacia

Croup

Bronchiolitis

Influenza

Pertussis (Whooping Cough)

Viral Pneumonia

A

epiglottitis:
- Haemophilus influenzae (MC)
- Streptococcal species in immunized patients

laryngomalacia: congenital

croup: Parainfluenza VIRUS

bronchiolitis: RSV

influenza: Influenza A/H1N1, A/H2N2

pertussis: Bordetella pertussis (bacterial infection)

viral PNA:
- Human rhinovirus
- adenovirus
- parainfluenza
- influenza
- coronavirus

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2
Q

Disease - etiology and appearance of rash

Measles (Rubeola)

Rubella (German Measles)

Erythema Infectiosum (5th Disease)

Roseola Infantum (6th Disease)

Varicella (Chickenpox)

Hand-Foot-Mouth Disease

A

Disease

Cause

Appearance of Rash

Measles (Rubeola): Paramyxovirus
- Prodrome: CCC + kolpik spots
- Rash: Maculopapular, starts on face → spreads downward

Rubella (German Measles)
- Togavirus
- Maculopapular, face → trunk, disappears in 3 days

Erythema Infectiosum (5th Disease)
- Parvovirus B19
- Low grade illness: fever, myalgia, headache -> rash
3 stages:
- “Slapped Cheek” rash, lacy, reticulated on trunk
- 1-4 days later: erythematous symmetric maculopapular rash on TRUNK
- Central clearing of rash

Roseola Infantum (6th Disease)
- HHV-6
- High fever resolves→ Rash - maculopapular rose-colored rash
- Varicella (Chickenpox)

Varicella-Zoster (VZV) double stranded DNA virus
- Prodrome: fever, malaise for 1 day before rash
Rash: Dew drop on a rose petal, vesicular, lesions at different stages
- Small red papules, non-umbilicated
- Start on trunk then head and extremities

Hand-Foot-Mouth Disease
- Coxsackievirus A5, 10, 16
- Vesicles/ red papules on palms, soles, oral mucosa

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3
Q

Disease - lab findings

Measles (Rubeola)

Rubella (German Measles)

Erythema Infectiosum (5th Disease)

Roseola Infantum (6th Disease)

Varicella (Chickenpox)

Hand-Foot-Mouth Disease

A

Measles:
- Serology: IgM appears 1-2 into rash

Rubella:
- IgM 5 days after onset
- 4x rise in IgG during acute phase

5th disease:
- Reticulocytopenia
- Thrombocytopenia
- Lymphopenia
- neutropenia
- Parvovirus B19 IgM
- PCR: erythroid precursors in bone marrow

roseola:
- PCR for HHV-6

chickenpox:
- PCR of vesicular fluid - VZV

HFM disease: Clinical Dx

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4
Q

epiglottitis vs croup tx

A

Epiglottitis : Haemophilus influenzae (MC)
* ET intubation for airway and extubation within 1-2 days when epiglottis reduced in size
* Blood and epiglottis culture
* IV ceftriaxone x2-3 days; followed by PO ab x 10 days

Croup: Parainfluenza
* Mild: supportive, hydrate, dexamethasone
* Severe (stridor at rest): nebulized racemic epinephrine diluted in sterile saline (refrigerated)
* - observe for 3-4 hrs -> discharge w no sx
* - Recurrent epi doses required -> admission for observation
* Impending respiratory failure: intubation with ET tube, extubation in 2-3 days

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5
Q

tx of bronchiolitis and influenza and viral PNA

A

Bronchiolitis:
- RSV
- supportive tx
- Hospitalize if respiratory distress, apnea, cannot tolerate oral feeding

Influenza:
- Supportive, Antivirals (Oseltamivir) if started within 48 hours

viral PNA:
- Supportive care; no antibiotics needed
- Human rhinovirus, adenovirus, parainfluenza, influenza, coronavirus

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6
Q

tx of pertussis and mycoplasma PNA

A

Pertussis :
- Bordetella pertussis
- Macrolide antibiotics (Azithromycin, Clarithromycin, Erythromycin)

mycoplasma:
- mycoplasma pneumoniae
- Macrolide antibiotics x 5-10 days

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7
Q

tx of bacterial and mycoplasma PNA

A

bacterial
- Under 4 wks old: ampicillin + aminoglycosides
- 4 wks - 6 months: IV ampicillin x 7-10 days
- Over 6 months: high dose amoxicillin TID x 7 days

mycoplasma
- Macrolide antibiotics x 5-10 days

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8
Q

fb aspiration tx

A

Prevention - counsel pts parents
Upper airway obstruction:
- Partial: cough reflex
- Complete: BLS protocol - 5 back sweeps and sternum presses, CPR if unresponsive
Lower airway:
- Rigid bronchoscopy under general anesthesia
- Beta neb tx

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