Jrcalc - Drug Know How Flashcards
What is the presentation of midazolam
Oral solution
2.5, 5, 7.5, 10mg
What is the max dose for ipratropium bromide
500mcg in 2ml
One max dose
What is the recommended oxygen need for effective nebulisation
6-8 litres
What is the dosage of ipratropium bromide
500mcg in 2ml
One dose = max dose
In COPD patients nebuliser should be limited to how much time
6 minutes before reassessment
Side effects of ipratropium bromide
Proxmal chest tightness
Allergic reaction
Tachycardia
Sickness
What is the action of ipratropium bromide
Bronchodilator - by working as a antimuscarinic
May have more benefit in paediatric asthma / adult COPD
What are the indicators for ipratropium bromide
Asthma - life threatening/ moderate
Asthma/ COPD - non responsive to salbutamol
Ibuprofen can be given with caution in which patient apart from asthma patients
Chron/ ulcerative colitis - may cause exacerbation
Patient with coagulation problems
Hypertension
what are the Contraindications for ibuprofen
Hypovolemic
Kidney problems
Gi problem - ulcers
Pregnancy - last 1/3
Chickenpox (children)
Allergic
If they had any other NSAID
What should a clinician make sure a patient has eaten before giving ibuprofen.(NSAID)
As this drug disrupts the gastric lining causing ulcers - eat first = that creates a barrier
What drug should be given to asthma patient with caution
Asprin and ibuprofen (NSAIDS) due to chance of bronchoconstriction
What are the action of ibuprofen
Anti-pyrexia
Analgesia
Anti inflammatory*****
What is the indicator for ibuprofen
Pain
Pyrexia with discomfort
Soft tissue injury’s
What is the maximum dosage for ibuprofen
1.2g
3× 400mg dosage = 1.2g
3 dosage in a 24hour period
What is the dosage interval for ibuprofen
8 hours
What is the dosage of ibuprofen
400mg
Is there a repeat dosage after the initial 200mg of hydrocortisone in patient with anaphylaxis
No
One max dose
Is there a repeat dosage after the initial 100mg of hydrocortisone in patient with life threatening asthma
No
One max dose
What is the dosage of hydrocortisone for patients in anaphylaxis
200mg in 2ml
200mg in 4ml
What is the dosage of hydrocortisone of patients in life threatening asthma
100mg given over 2 minutes IV PREFERABLY
Or
IM
Is there a toxic dose for hydrocortisone
No
HOWEVER
Under PGD’s there is a max dosage
Which patient should be administered IM hydrocortisone
Those with suspected adrenal insufficient
Those who are at risk of adrenal insufficient such as patients who are unwell due to long term steroid use
When should hydrocortisone be administered in patient with confirmed adrenal crisis
As soon as - prior to conveyance
If the clinician is unsure if the patient is suffering from adrenal insufficient- should they administer hydrocortisone
Yes - preferably intra muscular
How should hydrocortisone be administered in patient with confirmed adrenal crisis
Intravenous
What are the indicators for hydrocortisone
Anaphylaxis
Adrenal crisis / addersonian crisis
Life threatening asthma
What is the dose interval of GTN for patient experience breathlessness due to heart failure (pulmonary odema )
5-10 minutes
How can you as the clinician increase the absorption rate of GTN
By ensuring oral mucosa is moiste
How is hydrocortisone prepared
100mg of hydrocortisone powder is mixed with 2ml of water
What must be considered and checked between dosages of GTN
Blood pressure - further dosage can only be given if blood pressure threshold are met
90mmgh for ACS
110mmcg for heart failure
What is the maximum dosage of GTN for patient experience breathlessness due to heart failure (pulmonary odema )
2.4mg which is equal to 6 sprays
400mcg ×6 = 2.4mg
What is the dosage of GTN for patient experience breathlessness due to heart failure (pulmonary odema )
400-800mcg = 1-2 sprays
What is the maximum dosage of GTN For patients experiencing ACS
No limit
What is the dosage interval for GTN in patient experience ACS
5-10 minutes
What is the dosage of GTN for patient experience ACS
400-800mcg which is equal to 1-2 sprays
Every 5-10 minutes along as BP is above 90mmgh systolic
What are the contraindications of GTN
to much GTN can cause cardiac arrest
Stopping vein (in) unconscious heart patient
S - stenosis (mitral / aortic)
V - volume (hypovolemia)
In
U - unconscious patients
H - head trauma
P - pressure - hypotensive
When should GTN be given with caution
Patient with suspected posterior or inferior wall myocardial infarction (MI) DUE TO right MAIN OCCULSION- WHICH AFFECT RIGHT VENTRICLE causing hypotension
What are the consequences of the action of GTN
Reduced Blood pressure
Reduced cardiac spasm
Reduced preload
What are the action of GTN
Vasodilation of :
Coronary arteries : reducing cardiac spasm
Veins : reducing pre-load
What are the indicator for GTN
Cardiac chest pain - angina / MI where the systolic BP is above 90mmgh
Breathlessness due to pulmonary odema in heart failure when systolic BP is above 110mmgh
Patient with suspect cocaine toxicity
What is the presentation of GTN and for bonus points - what does each subunit dose contain
Spray
Bonus point - each spray contain 400mcg
What does GTN stand for
Glycern trinitrate
What is the site of absorbution for GTN
Sublingual - under the tongue
What classification of drug is morphine
Opioid
What is the maximum dosage for glucose 40%
20g
What are the contraindications for glucose 10%
IM OR SUBCUT administration
Why should you flush the IV line after administrating glucose 10%
As glucose causes irritation to the vein if stagnant next to it
What is the administration site for glucose 40% - and for double point how is it ABSORBED
Oral - absorbed by buccal routes
Buccal = gums
What is the presentation of glucose 40%
Plastic tube - containing 25g
What is the indication for glucose 40%
hypoglycaemia where there isn’t any risk of aspirations or choking
How many dosages of glucose 10% maybe given. And what is the maximum dosage
3 dosages maybe give of 10g glucose mixed in 100ml = 300ml max
What is the dose interval of glucose 10%
5 minutes
What is the initial dosage of glucose 10%
10g glucose mixed in 100ml
If a hypoglycemic patient with a reduced GCS starts improving with glucose 10% - should glucose be continued
Glucose 10% should be titrated to normal GCS
If a unconscious hypoglycaemic patient hasn’t shown any improvement to glucose 10% when can a second dose be given.
5 minutes
How does glucose 10% work
By giving sugar/glucuse straight into the blood stream
What is the difference between glucose 10% and glucose 40%
10% is a liquid form
40% is gel form
What drug can be given to unconscious patient who are hypoglycaemic and aren’t responding to glucagon
Glucose 10%
When is glucose 10% indicated
in hypoglycaemia ( sugar level below 4.0) where glucose gel isn’t possible - rapid improvement is required
Unconscious patient with suspected hypoglycaemic cause
In patient who haven’t responded to to glucagon after 10 minutes
When is atropine indicated
Symptomatic bradycardia such as
Absolute bradycardia (40BPM OR LESS)
Bradycardia post ROSC
Inadequate perfusion -which causes confusion
What is the presentation of glucagon
1mg POWDER to be mixed with water
What is the dosage for glucagon
1mg
How can you check the effectiveness of glucagon
By checking blood sugar level after 10-15 mins
How many time can glucagon be administered
Once
When administration furosemide how long should it be transfused into the system
2 minutes
What is the preference of first line benzodiazepine to patients that are convulsing
Midazolam - as this save time due to diazepam has to be given IV/IO or rectally.
Midazolam can be administered buccal
Should benzodiazepine be given as a preventive measure
NEVER. patient MUST be convulsing to receive benzodiazepine
Why is it best practice to have a BVM on hand for patients that have ingested benzodiazepine or opioids
Due to the risk of respiratory arrest
How long do eclamptic convulsions have to last before diazepam can be administered
Start treatment if seizure last over 2-3 minutes.
What are the dosage of adminstration for chlorphenamine parentally
10mg in 1ml - only one max dose
What is the presentation of chlorphenamine
10mg in 1ml - ampoule
Presentation of adrenaline 1:1000
Ampoule - ready to draw up
Presentation of atropine
Ampoule - ready to draw up
What is a common side effect of benzodiazepine
Respiratory arrest - this is more common if the patient has had alcohol
Hypotension
What are the indicators for Chlorphenamine
Allergic reaction which fall short of anaphylaxis
Alleviate symptoms after initial treatment of anaphylaxis
Second plus dose for atropine
600mcg in 1ml
Initial dose of atropine
600mcg In 1ml
Route of administration of aspirin
Oral - dispersible or chewed
Route of administration of aspirin
Oral - dispersible or chewed
How should glucagon be administered
Intramuscular
When is glucagon indicated
Hypoglycaemia - known or suspected (in unconscious patients). Sugar level below 4.0
What is the dosage for furosemide
40mg in 4ml
What is the second dosage of diazepam for adults
10mg in 2ml
What classification of drug is available for paramedic to administer to patients that are convulsing (seizures)
Benzodiazepine
What are the indicators for Diazepam
Patient who have had convulsions which have lasted 5 minutes or more
Patient who have had 3 or more convulsions in an hour
Patient MUST be convulsing at time of administration
What is the dosage for benzylpenicillin parental (IV/ IO)
1.2 gram in 20ml
What are the contraindications for benzylpenicillin
Known severe allergic reaction -
simple rash doesn’t count as severe
Presentation of amiodarone
Prefilled syringe 💉
Actions of atropine
Blocks vagal activity
Improve A-V conduction
What are the different parental route for administration of chlorphenamine
IM, IV ,IO
What is the maximum dosage of diazepam for adults
20 milligrams
When is active charcoal indicated
When a toxin has been injected one hour prior to clinicians arrival or under direction of Toxbase
What is the first line treatment for hypoglycaemia
Glucose gel ( glucose 40%)
In which group of patients is glucagon sometimes ineffective
Young and elderly due to malnourished therefore lack of glycogen to turn to glucose
What is the pharmacological effect of glucagon
Converts glycogen to glucose
Which condition should be met to administer glucagon apart from hypoglycaemia
When glucose gel is ineffective or not possible to administer and IV isn’t possible (to administer glucose)